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R.<p0,p1,beta,gamma> = PolynomialRing(ZZ,4)
P=matrix(R,2,[1-p0,p0,1-p1,p1])
B=matrix(R,2,[beta,1,1,gamma])
M=P*B*P.transpose()
(M[0,0]-M[0,1]) == -(p0-p1)*((beta-1)*(1-p0)+p0*(1-gamma))
True