{ "cells": [ { "cell_type": "markdown", "metadata": {}, "source": [ "# CDS-102: Lab 7 Workbook\n", "## Name: \n", "### March 9, 2017" ] }, { "cell_type": "code", "execution_count": 1, "metadata": { "collapsed": false }, "outputs": [ { "name": "stderr", "output_type": "stream", "text": [ "Loading tidyverse: ggplot2\n", "Loading tidyverse: tibble\n", "Loading tidyverse: tidyr\n", "Loading tidyverse: readr\n", "Loading tidyverse: purrr\n", "Loading tidyverse: dplyr\n", "Conflicts with tidy packages ---------------------------------------------------\n", "filter(): dplyr, stats\n", "lag(): dplyr, stats\n" ] } ], "source": [ "# Run this code block to load the Tidyverse package\n", ".libPaths(new = \"~/Rlibs\")\n", "library(tidyverse)" ] }, { "cell_type": "code", "execution_count": 2, "metadata": { "collapsed": false }, "outputs": [ { "name": "stderr", "output_type": "stream", "text": [ "Parsed with column specification:\n", "cols(\n", " .default = col_double(),\n", " GID = col_character(),\n", " YORF = col_character(),\n", " NAME = col_character(),\n", " GWEIGHT = col_integer()\n", ")\n", "See spec(...) for full column specifications.\n" ] } ], "source": [ "# Import the dataset\n", "original_data <- read_csv(\"Brauer2008_Dataset1.csv\")" ] }, { "cell_type": "code", "execution_count": 3, "metadata": { "collapsed": false }, "outputs": [ { "data": { "text/html": [ "\n", "\n", "\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\t\n", "\n", "
GIDYORFNAMEGWEIGHTG0.05G0.1G0.15G0.2G0.25G0.3⋯L0.15L0.2L0.25L0.3U0.05U0.1U0.15U0.2U0.25U0.3
GENE1331X A_06_P5820 SFB2 || ER to Golgi transport || molecular function unknown || YNL049C || 1082129 1 -0.24 -0.13 -0.21 -0.15 -0.05 -0.05 ⋯ 0.13 0.20 0.17 0.11 -0.06 -0.26 -0.05 -0.28 -0.19 0.09
GENE4924X A_06_P5866 || biological process unknown || molecular function unknown || YNL095C || 1086222 1 0.28 0.13 -0.40 -0.48 -0.11 0.17 ⋯ 0.02 0.04 0.03 0.01 -1.02 -0.91 -0.59 -0.61 -0.17 0.18
GENE4690X A_06_P1834 QRI7 || proteolysis and peptidolysis || metalloendopeptidase activity || YDL104C || 1085955 1 -0.02 -0.27 -0.27 -0.02 0.24 0.25 ⋯ -0.07 -0.05 -0.13 -0.04 -0.91 -0.94 -0.42 -0.36 -0.49 -0.47
GENE1177X A_06_P4928 CFT2 || mRNA polyadenylylation* || RNA binding || YLR115W || 1081958 1 -0.33 -0.41 -0.24 -0.03 -0.03 0.00 ⋯ -0.05 0.02 0.00 0.08 -0.53 -0.51 -0.26 0.05 -0.14 -0.01
GENE511X A_06_P5620 SSO2 || vesicle fusion* || t-SNARE activity || YMR183C || 1081214 1 0.05 0.02 0.40 0.34 -0.13 -0.14 ⋯ 0.00 -0.11 0.04 0.01 -0.45 -0.09 -0.13 0.02 -0.09 -0.03
GENE2133X A_06_P5307 PSP2 || biological process unknown || molecular function unknown || YML017W || 1083036 1 -0.69 -0.03 0.23 0.20 0.00 -0.27 ⋯ 0.25 -0.21 0.12 -0.11 NA -0.65 0.09 0.06 -0.07 -0.10
GENE1002X A_06_P6258 RIB2 || riboflavin biosynthesis || pseudouridylate synthase activity* || YOL066C || 1081766 1 -0.55 -0.30 -0.12 -0.03 -0.16 -0.11 ⋯ 0.27 0.24 0.05 0.19 0.07 -0.31 -0.08 0.12 0.05 0.06
GENE5478X A_06_P7082 VMA13 || vacuolar acidification || hydrogen-transporting ATPase activity, rotational mechanism || YPR036W || 1086860 1 -0.75 -0.12 -0.07 0.02 -0.32 -0.41 ⋯ 0.15 0.15 0.00 0.03 -0.40 -0.02 0.26 0.31 0.14 0.11
GENE2065X A_06_P2554 EDC3 || deadenylylation-independent decapping || molecular function unknown || YEL015W || 1082963 1 -0.24 -0.22 0.14 0.06 0.00 -0.13 ⋯ 0.17 0.07 0.10 0.11 0.01 -0.16 0.07 0.20 0.02 0.10
GENE2440X A_06_P6431 VPS5 || protein retention in Golgi* || protein transporter activity || YOR069W || 1083389 1 -0.16 -0.38 0.05 0.14 -0.04 -0.01 ⋯ 0.11 0.00 0.02 0.09 -0.26 -0.13 -0.10 0.07 -0.04 -0.12
GENE4180X A_06_P6220 || biological process unknown || molecular function unknown || YOL029C || 1085380 1 -0.22 -0.18 0.27 0.18 0.03 -0.04 ⋯ -0.04 -0.13 -0.08 0.10 -0.02 0.04 0.16 0.02 -0.03 -0.22
GENE5247X A_06_P1410 AMN1 || negative regulation of exit from mitosis* || protein binding || YBR158W || 1086594 1 0.18 0.61 1.55 1.34 0.23 -0.03 ⋯ -0.35 -0.27 -0.07 -0.11 -1.15 0.41 0.28 0.00 0.17 -0.01
GENE2121X A_06_P2983 SCW11 || cytokinesis, completion of separation || glucan 1,3-beta-glucosidase activity || YGL028C || 1083024 1 -0.67 -0.47 1.16 1.05 -0.18 -0.68 ⋯ -0.11 0.01 -0.27 -0.51 -1.48 -0.43 -0.27 -0.32 -0.24 -0.15
GENE1985X A_06_P3720 DSE2 || cell wall organization and biogenesis* || glucan 1,3-beta-glucosidase activity || YHR143W || 1082870 1 -0.59 -0.17 1.17 0.85 -0.12 -0.61 ⋯ -0.39 -0.42 -0.48 -0.65 -1.24 0.41 0.18 0.09 0.13 -0.04
GENE4728X A_06_P2774 COX15 || cytochrome c oxidase complex assembly* || oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor || YER141W || 1085995 1 -0.28 -0.81 -0.39 0.24 0.01 0.01 ⋯ -0.18 -0.02 0.15 -0.18 -1.91 -0.31 0.09 -0.24 -0.03 0.19
GENE3153X A_06_P4597 SPE1 || pantothenate biosynthesis* || ornithine decarboxylase activity || YKL184W || 1084207 1 -0.19 0.24 0.03 0.17 0.00 -0.01 ⋯ 0.04 -0.07 0.06 -0.20 -1.53 -0.43 -0.46 -0.73 -0.48 -0.25
GENE3704X A_06_P5667 MTF1 || transcription from mitochondrial promoter || S-adenosylmethionine-dependent methyltransferase activity* || YMR228W || 1084832 1 -0.42 -0.43 -0.36 -0.12 0.05 0.24 ⋯ -0.07 -0.14 -0.03 -0.04 -0.62 -0.53 -0.30 -0.17 -0.44 -0.35
GENE2141X A_06_P3260 KSS1 || invasive growth (sensu Saccharomyces)* || MAP kinase activity || YGR040W || 1083046 1 -0.76 -0.32 -0.05 -0.27 -0.31 -0.01 ⋯ 0.15 0.06 0.20 -0.11 -0.80 -0.18 -0.05 -0.26 -0.58 -0.18
GENE2978X A_06_P3607 || biological process unknown || molecular function unknown || YHR036W || 1084002 1 -0.91 -0.43 -0.05 -0.09 -0.27 -0.45 ⋯ -0.08 -0.12 -0.13 -0.05 -1.04 -0.59 -0.47 -0.29 -0.33 -0.20
GENE1203X A_06_P5929 || biological process unknown || molecular function unknown || YNL158W || 1081987 1 -0.47 -0.43 -0.15 0.08 -0.26 -0.25 ⋯ 0.02 -0.17 -0.30 -0.41 -0.67 -0.01 -0.20 -0.36 -0.30 -0.04
GENE3214X A_06_P6219 YAP7 || positive regulation of transcription from RNA polymerase II promoter || RNA polymerase II transcription factor activity || YOL028C || 10842811 -0.51 -0.04 0.06 0.26 -0.19 -0.22 ⋯ -0.16 -0.13 -0.13 -0.03 -1.09 -0.26 0.02 -0.09 -0.43 -0.21
GENE443X A_06_P1322 || proteolysis and peptidolysis || metalloendopeptidase activity || YBR074W || 1081132 1 -1.01 -0.55 -0.72 -0.54 -0.55 -0.19 ⋯ -0.08 -0.25 0.12 -0.09 NA -0.23 -0.32 -0.49 0.01 0.24
GENE1570X A_06_P6449 YVC1 || cation homeostasis || calcium channel activity* || YOR087W || 1082401 1 -0.40 -0.14 -0.06 0.00 -0.22 -0.07 ⋯ -0.10 -0.15 0.03 0.09 NA -0.39 -0.30 -0.28 -0.01 0.14
GENE4434X A_06_P2356 CDC40 || nuclear mRNA splicing, via spliceosome* || RNA splicing factor activity, transesterification mechanism* || YDR364C || 1085655 1 -0.19 -0.08 -0.16 -0.10 -0.12 -0.10 ⋯ -0.38 -0.19 -0.01 0.01 -1.07 -0.01 0.05 -0.10 -0.04 0.12
GENE2486X A_06_P6921 || biological process unknown || molecular function unknown || YPL162C || 1083440 1 -0.10 -0.02 -0.37 -0.09 -0.14 0.10 ⋯ -0.22 -0.04 -0.10 0.05 -1.19 0.15 -0.09 -0.17 0.05 0.12
GENE2099X A_06_P1729 RMD1 || biological process unknown || molecular function unknown || YDL001W || 1083001 1 -0.22 -0.03 -0.26 -0.19 -0.10 0.15 ⋯ -0.21 -0.16 -0.10 -0.03 -0.76 -0.03 -0.13 -0.20 -0.13 -0.03
GENE5137X A_06_P2688 PCL6 || regulation of glycogen biosynthesis* || cyclin-dependent protein kinase regulator activity || YER059W || 1086466 1 -0.25 -0.35 0.04 0.15 0.02 0.09 ⋯ 0.12 0.02 0.04 0.13 -1.10 -0.19 -0.12 0.08 0.00 0.06
GENE2691X A_06_P1007 AI4 || RNA splicing* || endonuclease activity || Q0065 || 1083679 1 -0.36 -0.39 0.42 -0.09 0.00 0.12 ⋯ 0.49 0.22 -0.09 -0.80 -1.59 -1.24 -0.65 -0.62 -0.61 -0.81
GENE2673X A_06_P1933 GGC1 || mitochondrial genome maintenance* || guanine nucleotide transporter activity || YDL198C || 1083659 1 0.76 0.33 -0.21 -0.16 0.00 0.09 ⋯ -0.15 -0.08 -0.72 -1.25 -2.31 -1.70 -1.37 -1.24 -0.73 -0.83
GENE3094X A_06_P1548 SUL1 || sulfate transport || sulfate transporter activity || YBR294W || 1084134 1 -0.32 -0.54 -0.37 -0.64 -0.09 -0.10 ⋯ -0.56 -0.77 -0.95 -1.32 -5.55 -4.59 -3.34 -1.98 -3.09 -1.79
⋮⋮⋮⋮⋮⋮⋮⋮⋮⋮⋱⋮⋮⋮⋮⋮⋮⋮⋮⋮⋮
GENE5335X A_06_P5817 || biological process unknown || molecular function unknown || YNL046W || 1086698 1 0.09 0.23 0.13 0.27 0.11 -0.08 ⋯ 0.02 0.25 0.10 -0.03 -0.13 0.56 0.39 0.38 0.40 0.36
GENE3931X A_06_P4860 RPS0B || protein biosynthesis* || structural constituent of ribosome || YLR048W || 1085091 1 -0.12 -0.42 -0.12 0.09 0.01 0.08 ⋯ 0.24 0.32 0.16 0.12 0.32 0.41 0.03 -0.12 0.16 0.30
GENE2273X A_06_P3220 COS12 || biological process unknown || molecular function unknown || YGL263W || 1083201 1 -1.30 0.09 0.29 -0.03 -0.14 -0.20 ⋯ 0.77 1.07 0.95 1.17 0.51 0.50 1.03 1.64 1.27 1.33
GENE1180X A_06_P6178 || biological process unknown || molecular function unknown || YNR065C || 1081961 1 -0.16 -0.02 0.15 0.17 -0.21 -0.12 ⋯ 0.13 -0.06 -0.21 -0.11 0.22 0.51 0.59 0.14 0.38 0.34
GENE4771X A_06_P2485 IZH1 || lipid metabolism* || metal ion binding || YDR492W || 1086044 1 -0.10 -0.13 0.28 0.46 0.23 -0.25 ⋯ -0.47 -0.62 -0.60 -0.51 0.39 0.35 0.31 -0.07 0.56 0.44
GENE321X A_06_P7110 || || || YPR064W || 1080987 1 0.13 0.17 0.53 1.21 0.38 -0.02 ⋯ -0.28 -0.11 -0.31 -0.37 1.21 1.54 0.93 0.50 0.52 0.27
GENE236X A_06_P6294 IZH4 || lipid metabolism* || metal ion binding || YOL101C || 1080893 1 0.64 0.44 1.31 1.35 0.97 0.26 ⋯ -0.13 -0.73 -0.46 -0.42 3.36 2.87 2.25 2.00 2.32 1.15
GENE2516X A_06_P2042 PST1 || cell wall organization and biogenesis || molecular function unknown || YDR055W || 1083475 1 0.62 0.25 1.12 1.05 0.13 -0.12 ⋯ 0.28 0.15 -0.05 -0.29 1.95 2.00 1.40 0.50 0.81 0.64
GENE1687X A_06_P4130 PRM10 || conjugation with cellular fusion || molecular function unknown || YJL108C || 1082535 1 0.63 0.59 0.73 0.65 0.23 0.29 ⋯ -0.24 -0.40 -0.42 -0.08 0.54 1.26 0.77 0.61 0.82 0.54
GENE5522X A_06_P4129 || biological process unknown || molecular function unknown || YJL107C || 1086909 1 0.65 0.62 0.71 0.71 0.04 0.10 ⋯ -0.29 -0.56 -0.73 -0.21 NA 1.06 0.58 0.39 0.53 0.48
GENE2461X A_06_P1902 SFA1 || formaldehyde catabolism || alcohol dehydrogenase activity* || YDL168W || 1083412 1 0.81 0.30 0.16 0.36 0.38 0.37 ⋯ -0.07 -0.01 -0.09 0.01 0.12 0.53 0.41 0.02 0.40 0.32
GENE5154X A_06_P3834 CAP2 || filamentous growth* || actin filament binding || YIL034C || 1086485 1 0.10 -0.33 0.05 0.25 0.09 -0.05 ⋯ 0.24 0.12 -0.01 -0.05 0.09 0.76 0.35 0.04 0.20 0.14
GENE2896X A_06_P5553 || biological process unknown || molecular function unknown || YMR122W-A || 1083907 1 0.01 -0.22 0.67 0.72 0.36 0.04 ⋯ -0.19 0.10 0.02 0.05 -0.06 0.87 0.88 0.28 0.49 0.49
GENE4037X A_06_P4180 CIS3 || cell wall organization and biogenesis || structural constituent of cell wall || YJL158C || 1085216 1 -0.01 -0.21 0.20 0.60 0.48 0.18 ⋯ -0.02 -0.06 0.07 0.03 0.49 1.47 1.13 0.04 0.69 0.32
GENE674X A_06_P7057 || || || YPR012W || 1081403 1 -0.23 0.05 0.25 0.28 0.22 0.27 ⋯ -0.14 0.02 0.13 0.04 0.32 0.14 -0.01 0.17 0.02 0.27
GENE3957X A_06_P6469 RGS2 || G-protein signaling, coupled to cAMP nucleotide second messenger || GTPase activator activity || YOR107W || 1085121 1 0.00 0.01 -0.13 0.02 -0.07 -0.32 ⋯ -0.09 -0.32 -0.30 -0.29 0.45 0.24 0.18 -0.24 -0.26 -0.08
GENE2250X A_06_P7164 || biological process unknown || molecular function unknown || YPR117W || 1083173 1 -0.22 -0.51 0.28 0.32 0.00 -0.38 ⋯ -0.49 -0.57 -0.53 -0.48 0.79 1.04 0.32 -0.14 0.29 -0.16
GENE785X A_06_P7198 || || || YPR150W || 1081527 1 -0.10 -0.24 -0.06 -0.04 -0.37 -0.67 ⋯ -0.21 -0.16 -0.17 -0.52 -0.13 0.67 0.39 -0.11 0.33 0.09
GENE4483X A_06_P1283 CSG2 || calcium ion homeostasis* || enzyme regulator activity || YBR036C || 1085710 1 0.06 -0.22 -0.09 0.15 -0.12 -0.27 ⋯ 0.15 0.16 0.03 -0.15 0.11 0.26 -0.04 -0.24 -0.05 -0.01
GENE491X A_06_P3540 SPO11 || meiotic DNA double-strand break formation || endodeoxyribonuclease activity, producing 3'-phosphomonoesters || YHL022C || 10811881 -0.83 0.21 0.04 -0.19 -0.41 -0.15 ⋯ 0.04 0.27 -0.17 -0.23 NA 0.07 0.33 0.19 0.01 -0.34
GENE4050X A_06_P2650 CHO1 || phosphatidylserine biosynthesis || CDP-diacylglycerol-serine O-phosphatidyltransferase activity || YER026C || 1085231 1 -0.74 -0.63 -0.07 0.11 -0.18 -0.31 ⋯ 0.26 0.11 0.04 -0.16 -0.28 0.81 -0.10 -0.03 -0.13 -0.20
GENE17X A_06_P6055 WSC2 || cell wall organization and biogenesis* || transmembrane receptor activity || YNL283C || 1080641 1 -0.62 -0.26 -0.19 -0.03 -0.09 -0.27 ⋯ -0.33 -0.21 -0.16 -0.20 0.67 0.78 0.08 -0.34 -0.09 -0.21
GENE4426X A_06_P6690 MYO2 || endocytosis* || microfilament motor activity || YOR326W || 1085645 1 -0.67 -0.38 -0.12 -0.05 -0.15 -0.24 ⋯ -0.12 -0.24 -0.15 -0.24 0.11 0.69 0.36 -0.12 0.08 -0.04
GENE1274X A_06_P6825 || biological process unknown || molecular function unknown || YPL066W || 1082066 1 -0.14 0.06 0.78 0.81 0.30 0.14 ⋯ 0.28 0.13 0.30 0.06 -0.75 1.91 0.47 0.25 0.37 0.15
GENE410X A_06_P4625 DOA1 || ubiquitin-dependent protein catabolism* || molecular function unknown || YKL213C || 1081094 1 0.12 -0.07 0.14 0.29 0.17 0.09 ⋯ 0.19 0.17 0.03 0.02 0.16 0.28 0.36 0.22 0.29 0.14
GENE2833X A_06_P6094 KRE1 || cell wall organization and biogenesis || structural constituent of cell wall || YNL322C || 1083836 1 0.41 -0.28 0.30 0.50 -0.05 -0.08 ⋯ 0.38 0.23 0.21 0.15 0.32 0.62 0.54 0.01 0.56 0.28
GENE271X A_06_P3243 MTL1 || cell wall organization and biogenesis || molecular function unknown || YGR023W || 1080930 1 0.50 -0.12 0.25 0.24 0.13 0.02 ⋯ 0.25 -0.02 -0.06 -0.10 NA 0.50 0.29 -0.14 0.47 0.27
GENE1691X A_06_P4196 KRE9 || cell wall organization and biogenesis* || molecular function unknown || YJL174W || 1082539 1 0.15 0.09 0.21 0.46 0.19 -0.02 ⋯ 0.37 0.21 0.16 -0.01 -0.68 0.63 0.41 0.09 0.48 0.43
GENE1755X A_06_P4680 UTH1 || mitochondrion organization and biogenesis* || molecular function unknown || YKR042W || 1082610 1 0.63 0.38 0.05 0.12 0.13 -0.01 ⋯ -0.07 0.02 0.24 0.18 -0.89 0.19 0.03 0.04 0.13 0.19
GENE4255X A_06_P6304 || biological process unknown || molecular function unknown || YOL111C || 1085465 1 0.18 0.05 0.11 0.09 -0.02 0.03 ⋯ -0.07 -0.08 -0.02 -0.06 0.03 0.14 0.00 -0.21 0.07 0.04
\n" ], "text/latex": [ "\\begin{tabular}{r|llllllllllllllllllllllllllllllllllllllll}\n", " GID & YORF & NAME & GWEIGHT & G0.05 & G0.1 & G0.15 & G0.2 & G0.25 & G0.3 & ⋯ & L0.15 & L0.2 & L0.25 & L0.3 & U0.05 & U0.1 & U0.15 & U0.2 & U0.25 & U0.3\\\\\n", "\\hline\n", "\t GENE1331X & A\\_06\\_P5820 & SFB2 \\textbar{}\\textbar{} ER to Golgi transport \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YNL049C \\textbar{}\\textbar{} 1082129 & 1 & -0.24 & -0.13 & -0.21 & -0.15 & -0.05 & -0.05 & ⋯ & 0.13 & 0.20 & 0.17 & 0.11 & -0.06 & -0.26 & -0.05 & -0.28 & -0.19 & 0.09 \\\\\n", "\t GENE4924X & A\\_06\\_P5866 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YNL095C \\textbar{}\\textbar{} 1086222 & 1 & 0.28 & 0.13 & -0.40 & -0.48 & -0.11 & 0.17 & ⋯ & 0.02 & 0.04 & 0.03 & 0.01 & -1.02 & -0.91 & -0.59 & -0.61 & -0.17 & 0.18 \\\\\n", "\t GENE4690X & A\\_06\\_P1834 & QRI7 \\textbar{}\\textbar{} proteolysis and peptidolysis \\textbar{}\\textbar{} metalloendopeptidase activity \\textbar{}\\textbar{} YDL104C \\textbar{}\\textbar{} 1085955 & 1 & -0.02 & -0.27 & -0.27 & -0.02 & 0.24 & 0.25 & ⋯ & -0.07 & -0.05 & -0.13 & -0.04 & -0.91 & -0.94 & -0.42 & -0.36 & -0.49 & -0.47 \\\\\n", "\t GENE1177X & A\\_06\\_P4928 & CFT2 \\textbar{}\\textbar{} mRNA polyadenylylation* \\textbar{}\\textbar{} RNA binding \\textbar{}\\textbar{} YLR115W \\textbar{}\\textbar{} 1081958 & 1 & -0.33 & -0.41 & -0.24 & -0.03 & -0.03 & 0.00 & ⋯ & -0.05 & 0.02 & 0.00 & 0.08 & -0.53 & -0.51 & -0.26 & 0.05 & -0.14 & -0.01 \\\\\n", "\t GENE511X & A\\_06\\_P5620 & SSO2 \\textbar{}\\textbar{} vesicle fusion* \\textbar{}\\textbar{} t-SNARE activity \\textbar{}\\textbar{} YMR183C \\textbar{}\\textbar{} 1081214 & 1 & 0.05 & 0.02 & 0.40 & 0.34 & -0.13 & -0.14 & ⋯ & 0.00 & -0.11 & 0.04 & 0.01 & -0.45 & -0.09 & -0.13 & 0.02 & -0.09 & -0.03 \\\\\n", "\t GENE2133X & A\\_06\\_P5307 & PSP2 \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YML017W \\textbar{}\\textbar{} 1083036 & 1 & -0.69 & -0.03 & 0.23 & 0.20 & 0.00 & -0.27 & ⋯ & 0.25 & -0.21 & 0.12 & -0.11 & NA & -0.65 & 0.09 & 0.06 & -0.07 & -0.10 \\\\\n", "\t GENE1002X & A\\_06\\_P6258 & RIB2 \\textbar{}\\textbar{} riboflavin biosynthesis \\textbar{}\\textbar{} pseudouridylate synthase activity* \\textbar{}\\textbar{} YOL066C \\textbar{}\\textbar{} 1081766 & 1 & -0.55 & -0.30 & -0.12 & -0.03 & -0.16 & -0.11 & ⋯ & 0.27 & 0.24 & 0.05 & 0.19 & 0.07 & -0.31 & -0.08 & 0.12 & 0.05 & 0.06 \\\\\n", "\t GENE5478X & A\\_06\\_P7082 & VMA13 \\textbar{}\\textbar{} vacuolar acidification \\textbar{}\\textbar{} hydrogen-transporting ATPase activity, rotational mechanism \\textbar{}\\textbar{} YPR036W \\textbar{}\\textbar{} 1086860 & 1 & -0.75 & -0.12 & -0.07 & 0.02 & -0.32 & -0.41 & ⋯ & 0.15 & 0.15 & 0.00 & 0.03 & -0.40 & -0.02 & 0.26 & 0.31 & 0.14 & 0.11 \\\\\n", "\t GENE2065X & A\\_06\\_P2554 & EDC3 \\textbar{}\\textbar{} deadenylylation-independent decapping \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YEL015W \\textbar{}\\textbar{} 1082963 & 1 & -0.24 & -0.22 & 0.14 & 0.06 & 0.00 & -0.13 & ⋯ & 0.17 & 0.07 & 0.10 & 0.11 & 0.01 & -0.16 & 0.07 & 0.20 & 0.02 & 0.10 \\\\\n", "\t GENE2440X & A\\_06\\_P6431 & VPS5 \\textbar{}\\textbar{} protein retention in Golgi* \\textbar{}\\textbar{} protein transporter activity \\textbar{}\\textbar{} YOR069W \\textbar{}\\textbar{} 1083389 & 1 & -0.16 & -0.38 & 0.05 & 0.14 & -0.04 & -0.01 & ⋯ & 0.11 & 0.00 & 0.02 & 0.09 & -0.26 & -0.13 & -0.10 & 0.07 & -0.04 & -0.12 \\\\\n", "\t GENE4180X & A\\_06\\_P6220 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YOL029C \\textbar{}\\textbar{} 1085380 & 1 & -0.22 & -0.18 & 0.27 & 0.18 & 0.03 & -0.04 & ⋯ & -0.04 & -0.13 & -0.08 & 0.10 & -0.02 & 0.04 & 0.16 & 0.02 & -0.03 & -0.22 \\\\\n", "\t GENE5247X & A\\_06\\_P1410 & AMN1 \\textbar{}\\textbar{} negative regulation of exit from mitosis* \\textbar{}\\textbar{} protein binding \\textbar{}\\textbar{} YBR158W \\textbar{}\\textbar{} 1086594 & 1 & 0.18 & 0.61 & 1.55 & 1.34 & 0.23 & -0.03 & ⋯ & -0.35 & -0.27 & -0.07 & -0.11 & -1.15 & 0.41 & 0.28 & 0.00 & 0.17 & -0.01 \\\\\n", "\t GENE2121X & A\\_06\\_P2983 & SCW11 \\textbar{}\\textbar{} cytokinesis, completion of separation \\textbar{}\\textbar{} glucan 1,3-beta-glucosidase activity \\textbar{}\\textbar{} YGL028C \\textbar{}\\textbar{} 1083024 & 1 & -0.67 & -0.47 & 1.16 & 1.05 & -0.18 & -0.68 & ⋯ & -0.11 & 0.01 & -0.27 & -0.51 & -1.48 & -0.43 & -0.27 & -0.32 & -0.24 & -0.15 \\\\\n", "\t GENE1985X & A\\_06\\_P3720 & DSE2 \\textbar{}\\textbar{} cell wall organization and biogenesis* \\textbar{}\\textbar{} glucan 1,3-beta-glucosidase activity \\textbar{}\\textbar{} YHR143W \\textbar{}\\textbar{} 1082870 & 1 & -0.59 & -0.17 & 1.17 & 0.85 & -0.12 & -0.61 & ⋯ & -0.39 & -0.42 & -0.48 & -0.65 & -1.24 & 0.41 & 0.18 & 0.09 & 0.13 & -0.04 \\\\\n", "\t GENE4728X & A\\_06\\_P2774 & COX15 \\textbar{}\\textbar{} cytochrome c oxidase complex assembly* \\textbar{}\\textbar{} oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor \\textbar{}\\textbar{} YER141W \\textbar{}\\textbar{} 1085995 & 1 & -0.28 & -0.81 & -0.39 & 0.24 & 0.01 & 0.01 & ⋯ & -0.18 & -0.02 & 0.15 & -0.18 & -1.91 & -0.31 & 0.09 & -0.24 & -0.03 & 0.19 \\\\\n", "\t GENE3153X & A\\_06\\_P4597 & SPE1 \\textbar{}\\textbar{} pantothenate biosynthesis* \\textbar{}\\textbar{} ornithine decarboxylase activity \\textbar{}\\textbar{} YKL184W \\textbar{}\\textbar{} 1084207 & 1 & -0.19 & 0.24 & 0.03 & 0.17 & 0.00 & -0.01 & ⋯ & 0.04 & -0.07 & 0.06 & -0.20 & -1.53 & -0.43 & -0.46 & -0.73 & -0.48 & -0.25 \\\\\n", "\t GENE3704X & A\\_06\\_P5667 & MTF1 \\textbar{}\\textbar{} transcription from mitochondrial promoter \\textbar{}\\textbar{} S-adenosylmethionine-dependent methyltransferase activity* \\textbar{}\\textbar{} YMR228W \\textbar{}\\textbar{} 1084832 & 1 & -0.42 & -0.43 & -0.36 & -0.12 & 0.05 & 0.24 & ⋯ & -0.07 & -0.14 & -0.03 & -0.04 & -0.62 & -0.53 & -0.30 & -0.17 & -0.44 & -0.35 \\\\\n", "\t GENE2141X & A\\_06\\_P3260 & KSS1 \\textbar{}\\textbar{} invasive growth (sensu Saccharomyces)* \\textbar{}\\textbar{} MAP kinase activity \\textbar{}\\textbar{} YGR040W \\textbar{}\\textbar{} 1083046 & 1 & -0.76 & -0.32 & -0.05 & -0.27 & -0.31 & -0.01 & ⋯ & 0.15 & 0.06 & 0.20 & -0.11 & -0.80 & -0.18 & -0.05 & -0.26 & -0.58 & -0.18 \\\\\n", "\t GENE2978X & A\\_06\\_P3607 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YHR036W \\textbar{}\\textbar{} 1084002 & 1 & -0.91 & -0.43 & -0.05 & -0.09 & -0.27 & -0.45 & ⋯ & -0.08 & -0.12 & -0.13 & -0.05 & -1.04 & -0.59 & -0.47 & -0.29 & -0.33 & -0.20 \\\\\n", "\t GENE1203X & A\\_06\\_P5929 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YNL158W \\textbar{}\\textbar{} 1081987 & 1 & -0.47 & -0.43 & -0.15 & 0.08 & -0.26 & -0.25 & ⋯ & 0.02 & -0.17 & -0.30 & -0.41 & -0.67 & -0.01 & -0.20 & -0.36 & -0.30 & -0.04 \\\\\n", "\t GENE3214X & A\\_06\\_P6219 & YAP7 \\textbar{}\\textbar{} positive regulation of transcription from RNA polymerase II promoter \\textbar{}\\textbar{} RNA polymerase II transcription factor activity \\textbar{}\\textbar{} YOL028C \\textbar{}\\textbar{} 1084281 & 1 & -0.51 & -0.04 & 0.06 & 0.26 & -0.19 & -0.22 & ⋯ & -0.16 & -0.13 & -0.13 & -0.03 & -1.09 & -0.26 & 0.02 & -0.09 & -0.43 & -0.21 \\\\\n", "\t GENE443X & A\\_06\\_P1322 & \\textbar{}\\textbar{} proteolysis and peptidolysis \\textbar{}\\textbar{} metalloendopeptidase activity \\textbar{}\\textbar{} YBR074W \\textbar{}\\textbar{} 1081132 & 1 & -1.01 & -0.55 & -0.72 & -0.54 & -0.55 & -0.19 & ⋯ & -0.08 & -0.25 & 0.12 & -0.09 & NA & -0.23 & -0.32 & -0.49 & 0.01 & 0.24 \\\\\n", "\t GENE1570X & A\\_06\\_P6449 & YVC1 \\textbar{}\\textbar{} cation homeostasis \\textbar{}\\textbar{} calcium channel activity* \\textbar{}\\textbar{} YOR087W \\textbar{}\\textbar{} 1082401 & 1 & -0.40 & -0.14 & -0.06 & 0.00 & -0.22 & -0.07 & ⋯ & -0.10 & -0.15 & 0.03 & 0.09 & NA & -0.39 & -0.30 & -0.28 & -0.01 & 0.14 \\\\\n", "\t GENE4434X & A\\_06\\_P2356 & CDC40 \\textbar{}\\textbar{} nuclear mRNA splicing, via spliceosome* \\textbar{}\\textbar{} RNA splicing factor activity, transesterification mechanism* \\textbar{}\\textbar{} YDR364C \\textbar{}\\textbar{} 1085655 & 1 & -0.19 & -0.08 & -0.16 & -0.10 & -0.12 & -0.10 & ⋯ & -0.38 & -0.19 & -0.01 & 0.01 & -1.07 & -0.01 & 0.05 & -0.10 & -0.04 & 0.12 \\\\\n", "\t GENE2486X & A\\_06\\_P6921 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YPL162C \\textbar{}\\textbar{} 1083440 & 1 & -0.10 & -0.02 & -0.37 & -0.09 & -0.14 & 0.10 & ⋯ & -0.22 & -0.04 & -0.10 & 0.05 & -1.19 & 0.15 & -0.09 & -0.17 & 0.05 & 0.12 \\\\\n", "\t GENE2099X & A\\_06\\_P1729 & RMD1 \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YDL001W \\textbar{}\\textbar{} 1083001 & 1 & -0.22 & -0.03 & -0.26 & -0.19 & -0.10 & 0.15 & ⋯ & -0.21 & -0.16 & -0.10 & -0.03 & -0.76 & -0.03 & -0.13 & -0.20 & -0.13 & -0.03 \\\\\n", "\t GENE5137X & A\\_06\\_P2688 & PCL6 \\textbar{}\\textbar{} regulation of glycogen biosynthesis* \\textbar{}\\textbar{} cyclin-dependent protein kinase regulator activity \\textbar{}\\textbar{} YER059W \\textbar{}\\textbar{} 1086466 & 1 & -0.25 & -0.35 & 0.04 & 0.15 & 0.02 & 0.09 & ⋯ & 0.12 & 0.02 & 0.04 & 0.13 & -1.10 & -0.19 & -0.12 & 0.08 & 0.00 & 0.06 \\\\\n", "\t GENE2691X & A\\_06\\_P1007 & AI4 \\textbar{}\\textbar{} RNA splicing* \\textbar{}\\textbar{} endonuclease activity \\textbar{}\\textbar{} Q0065 \\textbar{}\\textbar{} 1083679 & 1 & -0.36 & -0.39 & 0.42 & -0.09 & 0.00 & 0.12 & ⋯ & 0.49 & 0.22 & -0.09 & -0.80 & -1.59 & -1.24 & -0.65 & -0.62 & -0.61 & -0.81 \\\\\n", "\t GENE2673X & A\\_06\\_P1933 & GGC1 \\textbar{}\\textbar{} mitochondrial genome maintenance* \\textbar{}\\textbar{} guanine nucleotide transporter activity \\textbar{}\\textbar{} YDL198C \\textbar{}\\textbar{} 1083659 & 1 & 0.76 & 0.33 & -0.21 & -0.16 & 0.00 & 0.09 & ⋯ & -0.15 & -0.08 & -0.72 & -1.25 & -2.31 & -1.70 & -1.37 & -1.24 & -0.73 & -0.83 \\\\\n", "\t GENE3094X & A\\_06\\_P1548 & SUL1 \\textbar{}\\textbar{} sulfate transport \\textbar{}\\textbar{} sulfate transporter activity \\textbar{}\\textbar{} YBR294W \\textbar{}\\textbar{} 1084134 & 1 & -0.32 & -0.54 & -0.37 & -0.64 & -0.09 & -0.10 & ⋯ & -0.56 & -0.77 & -0.95 & -1.32 & -5.55 & -4.59 & -3.34 & -1.98 & -3.09 & -1.79 \\\\\n", "\t ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋱ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮ & ⋮\\\\\n", "\t GENE5335X & A\\_06\\_P5817 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YNL046W \\textbar{}\\textbar{} 1086698 & 1 & 0.09 & 0.23 & 0.13 & 0.27 & 0.11 & -0.08 & ⋯ & 0.02 & 0.25 & 0.10 & -0.03 & -0.13 & 0.56 & 0.39 & 0.38 & 0.40 & 0.36 \\\\\n", "\t GENE3931X & A\\_06\\_P4860 & RPS0B \\textbar{}\\textbar{} protein biosynthesis* \\textbar{}\\textbar{} structural constituent of ribosome \\textbar{}\\textbar{} YLR048W \\textbar{}\\textbar{} 1085091 & 1 & -0.12 & -0.42 & -0.12 & 0.09 & 0.01 & 0.08 & ⋯ & 0.24 & 0.32 & 0.16 & 0.12 & 0.32 & 0.41 & 0.03 & -0.12 & 0.16 & 0.30 \\\\\n", "\t GENE2273X & A\\_06\\_P3220 & COS12 \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YGL263W \\textbar{}\\textbar{} 1083201 & 1 & -1.30 & 0.09 & 0.29 & -0.03 & -0.14 & -0.20 & ⋯ & 0.77 & 1.07 & 0.95 & 1.17 & 0.51 & 0.50 & 1.03 & 1.64 & 1.27 & 1.33 \\\\\n", "\t GENE1180X & A\\_06\\_P6178 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YNR065C \\textbar{}\\textbar{} 1081961 & 1 & -0.16 & -0.02 & 0.15 & 0.17 & -0.21 & -0.12 & ⋯ & 0.13 & -0.06 & -0.21 & -0.11 & 0.22 & 0.51 & 0.59 & 0.14 & 0.38 & 0.34 \\\\\n", "\t GENE4771X & A\\_06\\_P2485 & IZH1 \\textbar{}\\textbar{} lipid metabolism* \\textbar{}\\textbar{} metal ion binding \\textbar{}\\textbar{} YDR492W \\textbar{}\\textbar{} 1086044 & 1 & -0.10 & -0.13 & 0.28 & 0.46 & 0.23 & -0.25 & ⋯ & -0.47 & -0.62 & -0.60 & -0.51 & 0.39 & 0.35 & 0.31 & -0.07 & 0.56 & 0.44 \\\\\n", "\t GENE321X & A\\_06\\_P7110 & \\textbar{}\\textbar{} \\textbar{}\\textbar{} \\textbar{}\\textbar{} YPR064W \\textbar{}\\textbar{} 1080987 & 1 & 0.13 & 0.17 & 0.53 & 1.21 & 0.38 & -0.02 & ⋯ & -0.28 & -0.11 & -0.31 & -0.37 & 1.21 & 1.54 & 0.93 & 0.50 & 0.52 & 0.27 \\\\\n", "\t GENE236X & A\\_06\\_P6294 & IZH4 \\textbar{}\\textbar{} lipid metabolism* \\textbar{}\\textbar{} metal ion binding \\textbar{}\\textbar{} YOL101C \\textbar{}\\textbar{} 1080893 & 1 & 0.64 & 0.44 & 1.31 & 1.35 & 0.97 & 0.26 & ⋯ & -0.13 & -0.73 & -0.46 & -0.42 & 3.36 & 2.87 & 2.25 & 2.00 & 2.32 & 1.15 \\\\\n", "\t GENE2516X & A\\_06\\_P2042 & PST1 \\textbar{}\\textbar{} cell wall organization and biogenesis \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YDR055W \\textbar{}\\textbar{} 1083475 & 1 & 0.62 & 0.25 & 1.12 & 1.05 & 0.13 & -0.12 & ⋯ & 0.28 & 0.15 & -0.05 & -0.29 & 1.95 & 2.00 & 1.40 & 0.50 & 0.81 & 0.64 \\\\\n", "\t GENE1687X & A\\_06\\_P4130 & PRM10 \\textbar{}\\textbar{} conjugation with cellular fusion \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YJL108C \\textbar{}\\textbar{} 1082535 & 1 & 0.63 & 0.59 & 0.73 & 0.65 & 0.23 & 0.29 & ⋯ & -0.24 & -0.40 & -0.42 & -0.08 & 0.54 & 1.26 & 0.77 & 0.61 & 0.82 & 0.54 \\\\\n", "\t GENE5522X & A\\_06\\_P4129 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YJL107C \\textbar{}\\textbar{} 1086909 & 1 & 0.65 & 0.62 & 0.71 & 0.71 & 0.04 & 0.10 & ⋯ & -0.29 & -0.56 & -0.73 & -0.21 & NA & 1.06 & 0.58 & 0.39 & 0.53 & 0.48 \\\\\n", "\t GENE2461X & A\\_06\\_P1902 & SFA1 \\textbar{}\\textbar{} formaldehyde catabolism \\textbar{}\\textbar{} alcohol dehydrogenase activity* \\textbar{}\\textbar{} YDL168W \\textbar{}\\textbar{} 1083412 & 1 & 0.81 & 0.30 & 0.16 & 0.36 & 0.38 & 0.37 & ⋯ & -0.07 & -0.01 & -0.09 & 0.01 & 0.12 & 0.53 & 0.41 & 0.02 & 0.40 & 0.32 \\\\\n", "\t GENE5154X & A\\_06\\_P3834 & CAP2 \\textbar{}\\textbar{} filamentous growth* \\textbar{}\\textbar{} actin filament binding \\textbar{}\\textbar{} YIL034C \\textbar{}\\textbar{} 1086485 & 1 & 0.10 & -0.33 & 0.05 & 0.25 & 0.09 & -0.05 & ⋯ & 0.24 & 0.12 & -0.01 & -0.05 & 0.09 & 0.76 & 0.35 & 0.04 & 0.20 & 0.14 \\\\\n", "\t GENE2896X & A\\_06\\_P5553 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YMR122W-A \\textbar{}\\textbar{} 1083907 & 1 & 0.01 & -0.22 & 0.67 & 0.72 & 0.36 & 0.04 & ⋯ & -0.19 & 0.10 & 0.02 & 0.05 & -0.06 & 0.87 & 0.88 & 0.28 & 0.49 & 0.49 \\\\\n", "\t GENE4037X & A\\_06\\_P4180 & CIS3 \\textbar{}\\textbar{} cell wall organization and biogenesis \\textbar{}\\textbar{} structural constituent of cell wall \\textbar{}\\textbar{} YJL158C \\textbar{}\\textbar{} 1085216 & 1 & -0.01 & -0.21 & 0.20 & 0.60 & 0.48 & 0.18 & ⋯ & -0.02 & -0.06 & 0.07 & 0.03 & 0.49 & 1.47 & 1.13 & 0.04 & 0.69 & 0.32 \\\\\n", "\t GENE674X & A\\_06\\_P7057 & \\textbar{}\\textbar{} \\textbar{}\\textbar{} \\textbar{}\\textbar{} YPR012W \\textbar{}\\textbar{} 1081403 & 1 & -0.23 & 0.05 & 0.25 & 0.28 & 0.22 & 0.27 & ⋯ & -0.14 & 0.02 & 0.13 & 0.04 & 0.32 & 0.14 & -0.01 & 0.17 & 0.02 & 0.27 \\\\\n", "\t GENE3957X & A\\_06\\_P6469 & RGS2 \\textbar{}\\textbar{} G-protein signaling, coupled to cAMP nucleotide second messenger \\textbar{}\\textbar{} GTPase activator activity \\textbar{}\\textbar{} YOR107W \\textbar{}\\textbar{} 1085121 & 1 & 0.00 & 0.01 & -0.13 & 0.02 & -0.07 & -0.32 & ⋯ & -0.09 & -0.32 & -0.30 & -0.29 & 0.45 & 0.24 & 0.18 & -0.24 & -0.26 & -0.08 \\\\\n", "\t GENE2250X & A\\_06\\_P7164 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YPR117W \\textbar{}\\textbar{} 1083173 & 1 & -0.22 & -0.51 & 0.28 & 0.32 & 0.00 & -0.38 & ⋯ & -0.49 & -0.57 & -0.53 & -0.48 & 0.79 & 1.04 & 0.32 & -0.14 & 0.29 & -0.16 \\\\\n", "\t GENE785X & A\\_06\\_P7198 & \\textbar{}\\textbar{} \\textbar{}\\textbar{} \\textbar{}\\textbar{} YPR150W \\textbar{}\\textbar{} 1081527 & 1 & -0.10 & -0.24 & -0.06 & -0.04 & -0.37 & -0.67 & ⋯ & -0.21 & -0.16 & -0.17 & -0.52 & -0.13 & 0.67 & 0.39 & -0.11 & 0.33 & 0.09 \\\\\n", "\t GENE4483X & A\\_06\\_P1283 & CSG2 \\textbar{}\\textbar{} calcium ion homeostasis* \\textbar{}\\textbar{} enzyme regulator activity \\textbar{}\\textbar{} YBR036C \\textbar{}\\textbar{} 1085710 & 1 & 0.06 & -0.22 & -0.09 & 0.15 & -0.12 & -0.27 & ⋯ & 0.15 & 0.16 & 0.03 & -0.15 & 0.11 & 0.26 & -0.04 & -0.24 & -0.05 & -0.01 \\\\\n", "\t GENE491X & A\\_06\\_P3540 & SPO11 \\textbar{}\\textbar{} meiotic DNA double-strand break formation \\textbar{}\\textbar{} endodeoxyribonuclease activity, producing 3'-phosphomonoesters \\textbar{}\\textbar{} YHL022C \\textbar{}\\textbar{} 1081188 & 1 & -0.83 & 0.21 & 0.04 & -0.19 & -0.41 & -0.15 & ⋯ & 0.04 & 0.27 & -0.17 & -0.23 & NA & 0.07 & 0.33 & 0.19 & 0.01 & -0.34 \\\\\n", "\t GENE4050X & A\\_06\\_P2650 & CHO1 \\textbar{}\\textbar{} phosphatidylserine biosynthesis \\textbar{}\\textbar{} CDP-diacylglycerol-serine O-phosphatidyltransferase activity \\textbar{}\\textbar{} YER026C \\textbar{}\\textbar{} 1085231 & 1 & -0.74 & -0.63 & -0.07 & 0.11 & -0.18 & -0.31 & ⋯ & 0.26 & 0.11 & 0.04 & -0.16 & -0.28 & 0.81 & -0.10 & -0.03 & -0.13 & -0.20 \\\\\n", "\t GENE17X & A\\_06\\_P6055 & WSC2 \\textbar{}\\textbar{} cell wall organization and biogenesis* \\textbar{}\\textbar{} transmembrane receptor activity \\textbar{}\\textbar{} YNL283C \\textbar{}\\textbar{} 1080641 & 1 & -0.62 & -0.26 & -0.19 & -0.03 & -0.09 & -0.27 & ⋯ & -0.33 & -0.21 & -0.16 & -0.20 & 0.67 & 0.78 & 0.08 & -0.34 & -0.09 & -0.21 \\\\\n", "\t GENE4426X & A\\_06\\_P6690 & MYO2 \\textbar{}\\textbar{} endocytosis* \\textbar{}\\textbar{} microfilament motor activity \\textbar{}\\textbar{} YOR326W \\textbar{}\\textbar{} 1085645 & 1 & -0.67 & -0.38 & -0.12 & -0.05 & -0.15 & -0.24 & ⋯ & -0.12 & -0.24 & -0.15 & -0.24 & 0.11 & 0.69 & 0.36 & -0.12 & 0.08 & -0.04 \\\\\n", "\t GENE1274X & A\\_06\\_P6825 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YPL066W \\textbar{}\\textbar{} 1082066 & 1 & -0.14 & 0.06 & 0.78 & 0.81 & 0.30 & 0.14 & ⋯ & 0.28 & 0.13 & 0.30 & 0.06 & -0.75 & 1.91 & 0.47 & 0.25 & 0.37 & 0.15 \\\\\n", "\t GENE410X & A\\_06\\_P4625 & DOA1 \\textbar{}\\textbar{} ubiquitin-dependent protein catabolism* \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YKL213C \\textbar{}\\textbar{} 1081094 & 1 & 0.12 & -0.07 & 0.14 & 0.29 & 0.17 & 0.09 & ⋯ & 0.19 & 0.17 & 0.03 & 0.02 & 0.16 & 0.28 & 0.36 & 0.22 & 0.29 & 0.14 \\\\\n", "\t GENE2833X & A\\_06\\_P6094 & KRE1 \\textbar{}\\textbar{} cell wall organization and biogenesis \\textbar{}\\textbar{} structural constituent of cell wall \\textbar{}\\textbar{} YNL322C \\textbar{}\\textbar{} 1083836 & 1 & 0.41 & -0.28 & 0.30 & 0.50 & -0.05 & -0.08 & ⋯ & 0.38 & 0.23 & 0.21 & 0.15 & 0.32 & 0.62 & 0.54 & 0.01 & 0.56 & 0.28 \\\\\n", "\t GENE271X & A\\_06\\_P3243 & MTL1 \\textbar{}\\textbar{} cell wall organization and biogenesis \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YGR023W \\textbar{}\\textbar{} 1080930 & 1 & 0.50 & -0.12 & 0.25 & 0.24 & 0.13 & 0.02 & ⋯ & 0.25 & -0.02 & -0.06 & -0.10 & NA & 0.50 & 0.29 & -0.14 & 0.47 & 0.27 \\\\\n", "\t GENE1691X & A\\_06\\_P4196 & KRE9 \\textbar{}\\textbar{} cell wall organization and biogenesis* \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YJL174W \\textbar{}\\textbar{} 1082539 & 1 & 0.15 & 0.09 & 0.21 & 0.46 & 0.19 & -0.02 & ⋯ & 0.37 & 0.21 & 0.16 & -0.01 & -0.68 & 0.63 & 0.41 & 0.09 & 0.48 & 0.43 \\\\\n", "\t GENE1755X & A\\_06\\_P4680 & UTH1 \\textbar{}\\textbar{} mitochondrion organization and biogenesis* \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YKR042W \\textbar{}\\textbar{} 1082610 & 1 & 0.63 & 0.38 & 0.05 & 0.12 & 0.13 & -0.01 & ⋯ & -0.07 & 0.02 & 0.24 & 0.18 & -0.89 & 0.19 & 0.03 & 0.04 & 0.13 & 0.19 \\\\\n", "\t GENE4255X & A\\_06\\_P6304 & \\textbar{}\\textbar{} biological process unknown \\textbar{}\\textbar{} molecular function unknown \\textbar{}\\textbar{} YOL111C \\textbar{}\\textbar{} 1085465 & 1 & 0.18 & 0.05 & 0.11 & 0.09 & -0.02 & 0.03 & ⋯ & -0.07 & -0.08 & -0.02 & -0.06 & 0.03 & 0.14 & 0.00 & -0.21 & 0.07 & 0.04 \\\\\n", "\\end{tabular}\n" ], "text/markdown": [ "\n", "GID | YORF | NAME | GWEIGHT | G0.05 | G0.1 | G0.15 | G0.2 | G0.25 | G0.3 | ⋯ | L0.15 | L0.2 | L0.25 | L0.3 | U0.05 | U0.1 | U0.15 | U0.2 | U0.25 | U0.3 | \n", "|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|\n", "| GENE1331X | A_06_P5820 | SFB2 || ER to Golgi transport || molecular function unknown || YNL049C || 1082129 | 1 | -0.24 | -0.13 | -0.21 | -0.15 | -0.05 | -0.05 | ⋯ | 0.13 | 0.20 | 0.17 | 0.11 | -0.06 | -0.26 | -0.05 | -0.28 | -0.19 | 0.09 | \n", "| GENE4924X | A_06_P5866 | || biological process unknown || molecular function unknown || YNL095C || 1086222 | 1 | 0.28 | 0.13 | -0.40 | -0.48 | -0.11 | 0.17 | ⋯ | 0.02 | 0.04 | 0.03 | 0.01 | -1.02 | -0.91 | -0.59 | -0.61 | -0.17 | 0.18 | \n", "| GENE4690X | A_06_P1834 | QRI7 || proteolysis and peptidolysis || metalloendopeptidase activity || YDL104C || 1085955 | 1 | -0.02 | -0.27 | -0.27 | -0.02 | 0.24 | 0.25 | ⋯ | -0.07 | -0.05 | -0.13 | -0.04 | -0.91 | -0.94 | -0.42 | -0.36 | -0.49 | -0.47 | \n", "| GENE1177X | A_06_P4928 | CFT2 || mRNA polyadenylylation* || RNA binding || YLR115W || 1081958 | 1 | -0.33 | -0.41 | -0.24 | -0.03 | -0.03 | 0.00 | ⋯ | -0.05 | 0.02 | 0.00 | 0.08 | -0.53 | -0.51 | -0.26 | 0.05 | -0.14 | -0.01 | \n", "| GENE511X | A_06_P5620 | SSO2 || vesicle fusion* || t-SNARE activity || YMR183C || 1081214 | 1 | 0.05 | 0.02 | 0.40 | 0.34 | -0.13 | -0.14 | ⋯ | 0.00 | -0.11 | 0.04 | 0.01 | -0.45 | -0.09 | -0.13 | 0.02 | -0.09 | -0.03 | \n", "| GENE2133X | A_06_P5307 | PSP2 || biological process unknown || molecular function unknown || YML017W || 1083036 | 1 | -0.69 | -0.03 | 0.23 | 0.20 | 0.00 | -0.27 | ⋯ | 0.25 | -0.21 | 0.12 | -0.11 | NA | -0.65 | 0.09 | 0.06 | -0.07 | -0.10 | \n", "| GENE1002X | A_06_P6258 | RIB2 || riboflavin biosynthesis || pseudouridylate synthase activity* || YOL066C || 1081766 | 1 | -0.55 | -0.30 | -0.12 | -0.03 | -0.16 | -0.11 | ⋯ | 0.27 | 0.24 | 0.05 | 0.19 | 0.07 | -0.31 | -0.08 | 0.12 | 0.05 | 0.06 | \n", "| GENE5478X | A_06_P7082 | VMA13 || vacuolar acidification || hydrogen-transporting ATPase activity, rotational mechanism || YPR036W || 1086860 | 1 | -0.75 | -0.12 | -0.07 | 0.02 | -0.32 | -0.41 | ⋯ | 0.15 | 0.15 | 0.00 | 0.03 | -0.40 | -0.02 | 0.26 | 0.31 | 0.14 | 0.11 | \n", "| GENE2065X | A_06_P2554 | EDC3 || deadenylylation-independent decapping || molecular function unknown || YEL015W || 1082963 | 1 | -0.24 | -0.22 | 0.14 | 0.06 | 0.00 | -0.13 | ⋯ | 0.17 | 0.07 | 0.10 | 0.11 | 0.01 | -0.16 | 0.07 | 0.20 | 0.02 | 0.10 | \n", "| GENE2440X | A_06_P6431 | VPS5 || protein retention in Golgi* || protein transporter activity || YOR069W || 1083389 | 1 | -0.16 | -0.38 | 0.05 | 0.14 | -0.04 | -0.01 | ⋯ | 0.11 | 0.00 | 0.02 | 0.09 | -0.26 | -0.13 | -0.10 | 0.07 | -0.04 | -0.12 | \n", "| GENE4180X | A_06_P6220 | || biological process unknown || molecular function unknown || YOL029C || 1085380 | 1 | -0.22 | -0.18 | 0.27 | 0.18 | 0.03 | -0.04 | ⋯ | -0.04 | -0.13 | -0.08 | 0.10 | -0.02 | 0.04 | 0.16 | 0.02 | -0.03 | -0.22 | \n", "| GENE5247X | A_06_P1410 | AMN1 || negative regulation of exit from mitosis* || protein binding || YBR158W || 1086594 | 1 | 0.18 | 0.61 | 1.55 | 1.34 | 0.23 | -0.03 | ⋯ | -0.35 | -0.27 | -0.07 | -0.11 | -1.15 | 0.41 | 0.28 | 0.00 | 0.17 | -0.01 | \n", "| GENE2121X | A_06_P2983 | SCW11 || cytokinesis, completion of separation || glucan 1,3-beta-glucosidase activity || YGL028C || 1083024 | 1 | -0.67 | -0.47 | 1.16 | 1.05 | -0.18 | -0.68 | ⋯ | -0.11 | 0.01 | -0.27 | -0.51 | -1.48 | -0.43 | -0.27 | -0.32 | -0.24 | -0.15 | \n", "| GENE1985X | A_06_P3720 | DSE2 || cell wall organization and biogenesis* || glucan 1,3-beta-glucosidase activity || YHR143W || 1082870 | 1 | -0.59 | -0.17 | 1.17 | 0.85 | -0.12 | -0.61 | ⋯ | -0.39 | -0.42 | -0.48 | -0.65 | -1.24 | 0.41 | 0.18 | 0.09 | 0.13 | -0.04 | \n", "| GENE4728X | A_06_P2774 | COX15 || cytochrome c oxidase complex assembly* || oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor || YER141W || 1085995 | 1 | -0.28 | -0.81 | -0.39 | 0.24 | 0.01 | 0.01 | ⋯ | -0.18 | -0.02 | 0.15 | -0.18 | -1.91 | -0.31 | 0.09 | -0.24 | -0.03 | 0.19 | \n", "| GENE3153X | A_06_P4597 | SPE1 || pantothenate biosynthesis* || ornithine decarboxylase activity || YKL184W || 1084207 | 1 | -0.19 | 0.24 | 0.03 | 0.17 | 0.00 | -0.01 | ⋯ | 0.04 | -0.07 | 0.06 | -0.20 | -1.53 | -0.43 | -0.46 | -0.73 | -0.48 | -0.25 | \n", "| GENE3704X | A_06_P5667 | MTF1 || transcription from mitochondrial promoter || S-adenosylmethionine-dependent methyltransferase activity* || YMR228W || 1084832 | 1 | -0.42 | -0.43 | -0.36 | -0.12 | 0.05 | 0.24 | ⋯ | -0.07 | -0.14 | -0.03 | -0.04 | -0.62 | -0.53 | -0.30 | -0.17 | -0.44 | -0.35 | \n", "| GENE2141X | A_06_P3260 | KSS1 || invasive growth (sensu Saccharomyces)* || MAP kinase activity || YGR040W || 1083046 | 1 | -0.76 | -0.32 | -0.05 | -0.27 | -0.31 | -0.01 | ⋯ | 0.15 | 0.06 | 0.20 | -0.11 | -0.80 | -0.18 | -0.05 | -0.26 | -0.58 | -0.18 | \n", "| GENE2978X | A_06_P3607 | || biological process unknown || molecular function unknown || YHR036W || 1084002 | 1 | -0.91 | -0.43 | -0.05 | -0.09 | -0.27 | -0.45 | ⋯ | -0.08 | -0.12 | -0.13 | -0.05 | -1.04 | -0.59 | -0.47 | -0.29 | -0.33 | -0.20 | \n", "| GENE1203X | A_06_P5929 | || biological process unknown || molecular function unknown || YNL158W || 1081987 | 1 | -0.47 | -0.43 | -0.15 | 0.08 | -0.26 | -0.25 | ⋯ | 0.02 | -0.17 | -0.30 | -0.41 | -0.67 | -0.01 | -0.20 | -0.36 | -0.30 | -0.04 | \n", "| GENE3214X | A_06_P6219 | YAP7 || positive regulation of transcription from RNA polymerase II promoter || RNA polymerase II transcription factor activity || YOL028C || 1084281 | 1 | -0.51 | -0.04 | 0.06 | 0.26 | -0.19 | -0.22 | ⋯ | -0.16 | -0.13 | -0.13 | -0.03 | -1.09 | -0.26 | 0.02 | -0.09 | -0.43 | -0.21 | \n", "| GENE443X | A_06_P1322 | || proteolysis and peptidolysis || metalloendopeptidase activity || YBR074W || 1081132 | 1 | -1.01 | -0.55 | -0.72 | -0.54 | -0.55 | -0.19 | ⋯ | -0.08 | -0.25 | 0.12 | -0.09 | NA | -0.23 | -0.32 | -0.49 | 0.01 | 0.24 | \n", "| GENE1570X | A_06_P6449 | YVC1 || cation homeostasis || calcium channel activity* || YOR087W || 1082401 | 1 | -0.40 | -0.14 | -0.06 | 0.00 | -0.22 | -0.07 | ⋯ | -0.10 | -0.15 | 0.03 | 0.09 | NA | -0.39 | -0.30 | -0.28 | -0.01 | 0.14 | \n", "| GENE4434X | A_06_P2356 | CDC40 || nuclear mRNA splicing, via spliceosome* || RNA splicing factor activity, transesterification mechanism* || YDR364C || 1085655 | 1 | -0.19 | -0.08 | -0.16 | -0.10 | -0.12 | -0.10 | ⋯ | -0.38 | -0.19 | -0.01 | 0.01 | -1.07 | -0.01 | 0.05 | -0.10 | -0.04 | 0.12 | \n", "| GENE2486X | A_06_P6921 | || biological process unknown || molecular function unknown || YPL162C || 1083440 | 1 | -0.10 | -0.02 | -0.37 | -0.09 | -0.14 | 0.10 | ⋯ | -0.22 | -0.04 | -0.10 | 0.05 | -1.19 | 0.15 | -0.09 | -0.17 | 0.05 | 0.12 | \n", "| GENE2099X | A_06_P1729 | RMD1 || biological process unknown || molecular function unknown || YDL001W || 1083001 | 1 | -0.22 | -0.03 | -0.26 | -0.19 | -0.10 | 0.15 | ⋯ | -0.21 | -0.16 | -0.10 | -0.03 | -0.76 | -0.03 | -0.13 | -0.20 | -0.13 | -0.03 | \n", "| GENE5137X | A_06_P2688 | PCL6 || regulation of glycogen biosynthesis* || cyclin-dependent protein kinase regulator activity || YER059W || 1086466 | 1 | -0.25 | -0.35 | 0.04 | 0.15 | 0.02 | 0.09 | ⋯ | 0.12 | 0.02 | 0.04 | 0.13 | -1.10 | -0.19 | -0.12 | 0.08 | 0.00 | 0.06 | \n", "| GENE2691X | A_06_P1007 | AI4 || RNA splicing* || endonuclease activity || Q0065 || 1083679 | 1 | -0.36 | -0.39 | 0.42 | -0.09 | 0.00 | 0.12 | ⋯ | 0.49 | 0.22 | -0.09 | -0.80 | -1.59 | -1.24 | -0.65 | -0.62 | -0.61 | -0.81 | \n", "| GENE2673X | A_06_P1933 | GGC1 || mitochondrial genome maintenance* || guanine nucleotide transporter activity || YDL198C || 1083659 | 1 | 0.76 | 0.33 | -0.21 | -0.16 | 0.00 | 0.09 | ⋯ | -0.15 | -0.08 | -0.72 | -1.25 | -2.31 | -1.70 | -1.37 | -1.24 | -0.73 | -0.83 | \n", "| GENE3094X | A_06_P1548 | SUL1 || sulfate transport || sulfate transporter activity || YBR294W || 1084134 | 1 | -0.32 | -0.54 | -0.37 | -0.64 | -0.09 | -0.10 | ⋯ | -0.56 | -0.77 | -0.95 | -1.32 | -5.55 | -4.59 | -3.34 | -1.98 | -3.09 | -1.79 | \n", "| ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋱ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | ⋮ | \n", "| GENE5335X | A_06_P5817 | || biological process unknown || molecular function unknown || YNL046W || 1086698 | 1 | 0.09 | 0.23 | 0.13 | 0.27 | 0.11 | -0.08 | ⋯ | 0.02 | 0.25 | 0.10 | -0.03 | -0.13 | 0.56 | 0.39 | 0.38 | 0.40 | 0.36 | \n", "| GENE3931X | A_06_P4860 | RPS0B || protein biosynthesis* || structural constituent of ribosome || YLR048W || 1085091 | 1 | -0.12 | -0.42 | -0.12 | 0.09 | 0.01 | 0.08 | ⋯ | 0.24 | 0.32 | 0.16 | 0.12 | 0.32 | 0.41 | 0.03 | -0.12 | 0.16 | 0.30 | \n", "| GENE2273X | A_06_P3220 | COS12 || biological process unknown || molecular function unknown || YGL263W || 1083201 | 1 | -1.30 | 0.09 | 0.29 | -0.03 | -0.14 | -0.20 | ⋯ | 0.77 | 1.07 | 0.95 | 1.17 | 0.51 | 0.50 | 1.03 | 1.64 | 1.27 | 1.33 | \n", "| GENE1180X | A_06_P6178 | || biological process unknown || molecular function unknown || YNR065C || 1081961 | 1 | -0.16 | -0.02 | 0.15 | 0.17 | -0.21 | -0.12 | ⋯ | 0.13 | -0.06 | -0.21 | -0.11 | 0.22 | 0.51 | 0.59 | 0.14 | 0.38 | 0.34 | \n", "| GENE4771X | A_06_P2485 | IZH1 || lipid metabolism* || metal ion binding || YDR492W || 1086044 | 1 | -0.10 | -0.13 | 0.28 | 0.46 | 0.23 | -0.25 | ⋯ | -0.47 | -0.62 | -0.60 | -0.51 | 0.39 | 0.35 | 0.31 | -0.07 | 0.56 | 0.44 | \n", "| GENE321X | A_06_P7110 | || || || YPR064W || 1080987 | 1 | 0.13 | 0.17 | 0.53 | 1.21 | 0.38 | -0.02 | ⋯ | -0.28 | -0.11 | -0.31 | -0.37 | 1.21 | 1.54 | 0.93 | 0.50 | 0.52 | 0.27 | \n", "| GENE236X | A_06_P6294 | IZH4 || lipid metabolism* || metal ion binding || YOL101C || 1080893 | 1 | 0.64 | 0.44 | 1.31 | 1.35 | 0.97 | 0.26 | ⋯ | -0.13 | -0.73 | -0.46 | -0.42 | 3.36 | 2.87 | 2.25 | 2.00 | 2.32 | 1.15 | \n", "| GENE2516X | A_06_P2042 | PST1 || cell wall organization and biogenesis || molecular function unknown || YDR055W || 1083475 | 1 | 0.62 | 0.25 | 1.12 | 1.05 | 0.13 | -0.12 | ⋯ | 0.28 | 0.15 | -0.05 | -0.29 | 1.95 | 2.00 | 1.40 | 0.50 | 0.81 | 0.64 | \n", "| GENE1687X | A_06_P4130 | PRM10 || conjugation with cellular fusion || molecular function unknown || YJL108C || 1082535 | 1 | 0.63 | 0.59 | 0.73 | 0.65 | 0.23 | 0.29 | ⋯ | -0.24 | -0.40 | -0.42 | -0.08 | 0.54 | 1.26 | 0.77 | 0.61 | 0.82 | 0.54 | \n", "| GENE5522X | A_06_P4129 | || biological process unknown || molecular function unknown || YJL107C || 1086909 | 1 | 0.65 | 0.62 | 0.71 | 0.71 | 0.04 | 0.10 | ⋯ | -0.29 | -0.56 | -0.73 | -0.21 | NA | 1.06 | 0.58 | 0.39 | 0.53 | 0.48 | \n", "| GENE2461X | A_06_P1902 | SFA1 || formaldehyde catabolism || alcohol dehydrogenase activity* || YDL168W || 1083412 | 1 | 0.81 | 0.30 | 0.16 | 0.36 | 0.38 | 0.37 | ⋯ | -0.07 | -0.01 | -0.09 | 0.01 | 0.12 | 0.53 | 0.41 | 0.02 | 0.40 | 0.32 | \n", "| GENE5154X | A_06_P3834 | CAP2 || filamentous growth* || actin filament binding || YIL034C || 1086485 | 1 | 0.10 | -0.33 | 0.05 | 0.25 | 0.09 | -0.05 | ⋯ | 0.24 | 0.12 | -0.01 | -0.05 | 0.09 | 0.76 | 0.35 | 0.04 | 0.20 | 0.14 | \n", "| GENE2896X | A_06_P5553 | || biological process unknown || molecular function unknown || YMR122W-A || 1083907 | 1 | 0.01 | -0.22 | 0.67 | 0.72 | 0.36 | 0.04 | ⋯ | -0.19 | 0.10 | 0.02 | 0.05 | -0.06 | 0.87 | 0.88 | 0.28 | 0.49 | 0.49 | \n", "| GENE4037X | A_06_P4180 | CIS3 || cell wall organization and biogenesis || structural constituent of cell wall || YJL158C || 1085216 | 1 | -0.01 | -0.21 | 0.20 | 0.60 | 0.48 | 0.18 | ⋯ | -0.02 | -0.06 | 0.07 | 0.03 | 0.49 | 1.47 | 1.13 | 0.04 | 0.69 | 0.32 | \n", "| GENE674X | A_06_P7057 | || || || YPR012W || 1081403 | 1 | -0.23 | 0.05 | 0.25 | 0.28 | 0.22 | 0.27 | ⋯ | -0.14 | 0.02 | 0.13 | 0.04 | 0.32 | 0.14 | -0.01 | 0.17 | 0.02 | 0.27 | \n", "| GENE3957X | A_06_P6469 | RGS2 || G-protein signaling, coupled to cAMP nucleotide second messenger || GTPase activator activity || YOR107W || 1085121 | 1 | 0.00 | 0.01 | -0.13 | 0.02 | -0.07 | -0.32 | ⋯ | -0.09 | -0.32 | -0.30 | -0.29 | 0.45 | 0.24 | 0.18 | -0.24 | -0.26 | -0.08 | \n", "| GENE2250X | A_06_P7164 | || biological process unknown || molecular function unknown || YPR117W || 1083173 | 1 | -0.22 | -0.51 | 0.28 | 0.32 | 0.00 | -0.38 | ⋯ | -0.49 | -0.57 | -0.53 | -0.48 | 0.79 | 1.04 | 0.32 | -0.14 | 0.29 | -0.16 | \n", "| GENE785X | A_06_P7198 | || || || YPR150W || 1081527 | 1 | -0.10 | -0.24 | -0.06 | -0.04 | -0.37 | -0.67 | ⋯ | -0.21 | -0.16 | -0.17 | -0.52 | -0.13 | 0.67 | 0.39 | -0.11 | 0.33 | 0.09 | \n", "| GENE4483X | A_06_P1283 | CSG2 || calcium ion homeostasis* || enzyme regulator activity || YBR036C || 1085710 | 1 | 0.06 | -0.22 | -0.09 | 0.15 | -0.12 | -0.27 | ⋯ | 0.15 | 0.16 | 0.03 | -0.15 | 0.11 | 0.26 | -0.04 | -0.24 | -0.05 | -0.01 | \n", "| GENE491X | A_06_P3540 | SPO11 || meiotic DNA double-strand break formation || endodeoxyribonuclease activity, producing 3'-phosphomonoesters || YHL022C || 1081188 | 1 | -0.83 | 0.21 | 0.04 | -0.19 | -0.41 | -0.15 | ⋯ | 0.04 | 0.27 | -0.17 | -0.23 | NA | 0.07 | 0.33 | 0.19 | 0.01 | -0.34 | \n", "| GENE4050X | A_06_P2650 | CHO1 || phosphatidylserine biosynthesis || CDP-diacylglycerol-serine O-phosphatidyltransferase activity || YER026C || 1085231 | 1 | -0.74 | -0.63 | -0.07 | 0.11 | -0.18 | -0.31 | ⋯ | 0.26 | 0.11 | 0.04 | -0.16 | -0.28 | 0.81 | -0.10 | -0.03 | -0.13 | -0.20 | \n", "| GENE17X | A_06_P6055 | WSC2 || cell wall organization and biogenesis* || transmembrane receptor activity || YNL283C || 1080641 | 1 | -0.62 | -0.26 | -0.19 | -0.03 | -0.09 | -0.27 | ⋯ | -0.33 | -0.21 | -0.16 | -0.20 | 0.67 | 0.78 | 0.08 | -0.34 | -0.09 | -0.21 | \n", "| GENE4426X | A_06_P6690 | MYO2 || endocytosis* || microfilament motor activity || YOR326W || 1085645 | 1 | -0.67 | -0.38 | -0.12 | -0.05 | -0.15 | -0.24 | ⋯ | -0.12 | -0.24 | -0.15 | -0.24 | 0.11 | 0.69 | 0.36 | -0.12 | 0.08 | -0.04 | \n", "| GENE1274X | A_06_P6825 | || biological process unknown || molecular function unknown || YPL066W || 1082066 | 1 | -0.14 | 0.06 | 0.78 | 0.81 | 0.30 | 0.14 | ⋯ | 0.28 | 0.13 | 0.30 | 0.06 | -0.75 | 1.91 | 0.47 | 0.25 | 0.37 | 0.15 | \n", "| GENE410X | A_06_P4625 | DOA1 || ubiquitin-dependent protein catabolism* || molecular function unknown || YKL213C || 1081094 | 1 | 0.12 | -0.07 | 0.14 | 0.29 | 0.17 | 0.09 | ⋯ | 0.19 | 0.17 | 0.03 | 0.02 | 0.16 | 0.28 | 0.36 | 0.22 | 0.29 | 0.14 | \n", "| GENE2833X | A_06_P6094 | KRE1 || cell wall organization and biogenesis || structural constituent of cell wall || YNL322C || 1083836 | 1 | 0.41 | -0.28 | 0.30 | 0.50 | -0.05 | -0.08 | ⋯ | 0.38 | 0.23 | 0.21 | 0.15 | 0.32 | 0.62 | 0.54 | 0.01 | 0.56 | 0.28 | \n", "| GENE271X | A_06_P3243 | MTL1 || cell wall organization and biogenesis || molecular function unknown || YGR023W || 1080930 | 1 | 0.50 | -0.12 | 0.25 | 0.24 | 0.13 | 0.02 | ⋯ | 0.25 | -0.02 | -0.06 | -0.10 | NA | 0.50 | 0.29 | -0.14 | 0.47 | 0.27 | \n", "| GENE1691X | A_06_P4196 | KRE9 || cell wall organization and biogenesis* || molecular function unknown || YJL174W || 1082539 | 1 | 0.15 | 0.09 | 0.21 | 0.46 | 0.19 | -0.02 | ⋯ | 0.37 | 0.21 | 0.16 | -0.01 | -0.68 | 0.63 | 0.41 | 0.09 | 0.48 | 0.43 | \n", "| GENE1755X | A_06_P4680 | UTH1 || mitochondrion organization and biogenesis* || molecular function unknown || YKR042W || 1082610 | 1 | 0.63 | 0.38 | 0.05 | 0.12 | 0.13 | -0.01 | ⋯ | -0.07 | 0.02 | 0.24 | 0.18 | -0.89 | 0.19 | 0.03 | 0.04 | 0.13 | 0.19 | \n", "| GENE4255X | A_06_P6304 | || biological process unknown || molecular function unknown || YOL111C || 1085465 | 1 | 0.18 | 0.05 | 0.11 | 0.09 | -0.02 | 0.03 | ⋯ | -0.07 | -0.08 | -0.02 | -0.06 | 0.03 | 0.14 | 0.00 | -0.21 | 0.07 | 0.04 | \n", "\n", "\n" ], "text/plain": [ " GID YORF \n", "1 GENE1331X A_06_P5820\n", "2 GENE4924X A_06_P5866\n", "3 GENE4690X A_06_P1834\n", "4 GENE1177X A_06_P4928\n", "5 GENE511X A_06_P5620\n", "6 GENE2133X A_06_P5307\n", "7 GENE1002X A_06_P6258\n", "8 GENE5478X A_06_P7082\n", "9 GENE2065X A_06_P2554\n", "10 GENE2440X A_06_P6431\n", "11 GENE4180X A_06_P6220\n", "12 GENE5247X A_06_P1410\n", "13 GENE2121X A_06_P2983\n", "14 GENE1985X A_06_P3720\n", "15 GENE4728X A_06_P2774\n", "16 GENE3153X A_06_P4597\n", "17 GENE3704X A_06_P5667\n", "18 GENE2141X A_06_P3260\n", "19 GENE2978X A_06_P3607\n", "20 GENE1203X A_06_P5929\n", "21 GENE3214X A_06_P6219\n", "22 GENE443X A_06_P1322\n", "23 GENE1570X A_06_P6449\n", "24 GENE4434X A_06_P2356\n", "25 GENE2486X A_06_P6921\n", "26 GENE2099X A_06_P1729\n", "27 GENE5137X A_06_P2688\n", "28 GENE2691X A_06_P1007\n", "29 GENE2673X A_06_P1933\n", "30 GENE3094X A_06_P1548\n", "⋮ ⋮ ⋮ \n", "5508 GENE5335X A_06_P5817\n", "5509 GENE3931X A_06_P4860\n", "5510 GENE2273X A_06_P3220\n", "5511 GENE1180X A_06_P6178\n", "5512 GENE4771X A_06_P2485\n", "5513 GENE321X A_06_P7110\n", "5514 GENE236X A_06_P6294\n", "5515 GENE2516X A_06_P2042\n", "5516 GENE1687X A_06_P4130\n", "5517 GENE5522X A_06_P4129\n", "5518 GENE2461X A_06_P1902\n", "5519 GENE5154X A_06_P3834\n", "5520 GENE2896X A_06_P5553\n", "5521 GENE4037X A_06_P4180\n", "5522 GENE674X A_06_P7057\n", "5523 GENE3957X A_06_P6469\n", "5524 GENE2250X A_06_P7164\n", "5525 GENE785X A_06_P7198\n", "5526 GENE4483X A_06_P1283\n", "5527 GENE491X A_06_P3540\n", "5528 GENE4050X A_06_P2650\n", "5529 GENE17X A_06_P6055\n", "5530 GENE4426X A_06_P6690\n", "5531 GENE1274X A_06_P6825\n", "5532 GENE410X A_06_P4625\n", "5533 GENE2833X A_06_P6094\n", "5534 GENE271X A_06_P3243\n", "5535 GENE1691X A_06_P4196\n", "5536 GENE1755X A_06_P4680\n", "5537 GENE4255X A_06_P6304\n", " NAME \n", "1 SFB2 || ER to Golgi transport || molecular function unknown || YNL049C || 1082129 \n", "2 || biological process unknown || molecular function unknown || YNL095C || 1086222 \n", "3 QRI7 || proteolysis and peptidolysis || metalloendopeptidase activity || YDL104C || 1085955 \n", "4 CFT2 || mRNA polyadenylylation* || RNA binding || YLR115W || 1081958 \n", "5 SSO2 || vesicle fusion* || t-SNARE activity || YMR183C || 1081214 \n", "6 PSP2 || biological process unknown || molecular function unknown || YML017W || 1083036 \n", "7 RIB2 || riboflavin biosynthesis || pseudouridylate synthase activity* || YOL066C || 1081766 \n", "8 VMA13 || vacuolar acidification || hydrogen-transporting ATPase activity, rotational mechanism || YPR036W || 1086860 \n", "9 EDC3 || deadenylylation-independent decapping || molecular function unknown || YEL015W || 1082963 \n", "10 VPS5 || protein retention in Golgi* || protein transporter activity || YOR069W || 1083389 \n", "11 || biological process unknown || molecular function unknown || YOL029C || 1085380 \n", "12 AMN1 || negative regulation of exit from mitosis* || protein binding || YBR158W || 1086594 \n", "13 SCW11 || cytokinesis, completion of separation || glucan 1,3-beta-glucosidase activity || YGL028C || 1083024 \n", "14 DSE2 || cell wall organization and biogenesis* || glucan 1,3-beta-glucosidase activity || YHR143W || 1082870 \n", "15 COX15 || cytochrome c oxidase complex assembly* || oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor || YER141W || 1085995 \n", "16 SPE1 || pantothenate biosynthesis* || ornithine decarboxylase activity || YKL184W || 1084207 \n", "17 MTF1 || transcription from mitochondrial promoter || S-adenosylmethionine-dependent methyltransferase activity* || YMR228W || 1084832 \n", "18 KSS1 || invasive growth (sensu Saccharomyces)* || MAP kinase activity || YGR040W || 1083046 \n", "19 || biological process unknown || molecular function unknown || YHR036W || 1084002 \n", "20 || biological process unknown || molecular function unknown || YNL158W || 1081987 \n", "21 YAP7 || positive regulation of transcription from RNA polymerase II promoter || RNA polymerase II transcription factor activity || YOL028C || 1084281\n", "22 || proteolysis and peptidolysis || metalloendopeptidase activity || YBR074W || 1081132 \n", "23 YVC1 || cation homeostasis || calcium channel activity* || YOR087W || 1082401 \n", "24 CDC40 || nuclear mRNA splicing, via spliceosome* || RNA splicing factor activity, transesterification mechanism* || YDR364C || 1085655 \n", "25 || biological process unknown || molecular function unknown || YPL162C || 1083440 \n", "26 RMD1 || biological process unknown || molecular function unknown || YDL001W || 1083001 \n", "27 PCL6 || regulation of glycogen biosynthesis* || cyclin-dependent protein kinase regulator activity || YER059W || 1086466 \n", "28 AI4 || RNA splicing* || endonuclease activity || Q0065 || 1083679 \n", "29 GGC1 || mitochondrial genome maintenance* || guanine nucleotide transporter activity || YDL198C || 1083659 \n", "30 SUL1 || sulfate transport || sulfate transporter activity || YBR294W || 1084134 \n", "⋮ ⋮ \n", "5508 || biological process unknown || molecular function unknown || YNL046W || 1086698 \n", "5509 RPS0B || protein biosynthesis* || structural constituent of ribosome || YLR048W || 1085091 \n", "5510 COS12 || biological process unknown || molecular function unknown || YGL263W || 1083201 \n", "5511 || biological process unknown || molecular function unknown || YNR065C || 1081961 \n", "5512 IZH1 || lipid metabolism* || metal ion binding || YDR492W || 1086044 \n", "5513 || || || YPR064W || 1080987 \n", "5514 IZH4 || lipid metabolism* || metal ion binding || YOL101C || 1080893 \n", "5515 PST1 || cell wall organization and biogenesis || molecular function unknown || YDR055W || 1083475 \n", "5516 PRM10 || conjugation with cellular fusion || molecular function unknown || YJL108C || 1082535 \n", "5517 || biological process unknown || molecular function unknown || YJL107C || 1086909 \n", "5518 SFA1 || formaldehyde catabolism || alcohol dehydrogenase activity* || YDL168W || 1083412 \n", "5519 CAP2 || filamentous growth* || actin filament binding || YIL034C || 1086485 \n", "5520 || biological process unknown || molecular function unknown || YMR122W-A || 1083907 \n", "5521 CIS3 || cell wall organization and biogenesis || structural constituent of cell wall || YJL158C || 1085216 \n", "5522 || || || YPR012W || 1081403 \n", "5523 RGS2 || G-protein signaling, coupled to cAMP nucleotide second messenger || GTPase activator activity || YOR107W || 1085121 \n", "5524 || biological process unknown || molecular function unknown || YPR117W || 1083173 \n", "5525 || || || YPR150W || 1081527 \n", "5526 CSG2 || calcium ion homeostasis* || enzyme regulator activity || YBR036C || 1085710 \n", "5527 SPO11 || meiotic DNA double-strand break formation || endodeoxyribonuclease activity, producing 3'-phosphomonoesters || YHL022C || 1081188 \n", "5528 CHO1 || phosphatidylserine biosynthesis || CDP-diacylglycerol-serine O-phosphatidyltransferase activity || YER026C || 1085231 \n", "5529 WSC2 || cell wall organization and biogenesis* || transmembrane receptor activity || YNL283C || 1080641 \n", "5530 MYO2 || endocytosis* || microfilament motor activity || YOR326W || 1085645 \n", "5531 || biological process unknown || molecular function unknown || YPL066W || 1082066 \n", "5532 DOA1 || ubiquitin-dependent protein catabolism* || molecular function unknown || YKL213C || 1081094 \n", "5533 KRE1 || cell wall organization and biogenesis || structural constituent of cell wall || YNL322C || 1083836 \n", "5534 MTL1 || cell wall organization and biogenesis || molecular function unknown || YGR023W || 1080930 \n", "5535 KRE9 || cell wall organization and biogenesis* || molecular function unknown || YJL174W || 1082539 \n", "5536 UTH1 || mitochondrion organization and biogenesis* || molecular function unknown || YKR042W || 1082610 \n", "5537 || biological process unknown || molecular function unknown || YOL111C || 1085465 \n", " GWEIGHT G0.05 G0.1 G0.15 G0.2 G0.25 G0.3 ⋯ L0.15 L0.2 L0.25 L0.3 \n", "1 1 -0.24 -0.13 -0.21 -0.15 -0.05 -0.05 ⋯ 0.13 0.20 0.17 0.11\n", "2 1 0.28 0.13 -0.40 -0.48 -0.11 0.17 ⋯ 0.02 0.04 0.03 0.01\n", "3 1 -0.02 -0.27 -0.27 -0.02 0.24 0.25 ⋯ -0.07 -0.05 -0.13 -0.04\n", "4 1 -0.33 -0.41 -0.24 -0.03 -0.03 0.00 ⋯ -0.05 0.02 0.00 0.08\n", "5 1 0.05 0.02 0.40 0.34 -0.13 -0.14 ⋯ 0.00 -0.11 0.04 0.01\n", "6 1 -0.69 -0.03 0.23 0.20 0.00 -0.27 ⋯ 0.25 -0.21 0.12 -0.11\n", "7 1 -0.55 -0.30 -0.12 -0.03 -0.16 -0.11 ⋯ 0.27 0.24 0.05 0.19\n", "8 1 -0.75 -0.12 -0.07 0.02 -0.32 -0.41 ⋯ 0.15 0.15 0.00 0.03\n", "9 1 -0.24 -0.22 0.14 0.06 0.00 -0.13 ⋯ 0.17 0.07 0.10 0.11\n", "10 1 -0.16 -0.38 0.05 0.14 -0.04 -0.01 ⋯ 0.11 0.00 0.02 0.09\n", "11 1 -0.22 -0.18 0.27 0.18 0.03 -0.04 ⋯ -0.04 -0.13 -0.08 0.10\n", "12 1 0.18 0.61 1.55 1.34 0.23 -0.03 ⋯ -0.35 -0.27 -0.07 -0.11\n", "13 1 -0.67 -0.47 1.16 1.05 -0.18 -0.68 ⋯ -0.11 0.01 -0.27 -0.51\n", "14 1 -0.59 -0.17 1.17 0.85 -0.12 -0.61 ⋯ -0.39 -0.42 -0.48 -0.65\n", "15 1 -0.28 -0.81 -0.39 0.24 0.01 0.01 ⋯ -0.18 -0.02 0.15 -0.18\n", "16 1 -0.19 0.24 0.03 0.17 0.00 -0.01 ⋯ 0.04 -0.07 0.06 -0.20\n", "17 1 -0.42 -0.43 -0.36 -0.12 0.05 0.24 ⋯ -0.07 -0.14 -0.03 -0.04\n", "18 1 -0.76 -0.32 -0.05 -0.27 -0.31 -0.01 ⋯ 0.15 0.06 0.20 -0.11\n", "19 1 -0.91 -0.43 -0.05 -0.09 -0.27 -0.45 ⋯ -0.08 -0.12 -0.13 -0.05\n", "20 1 -0.47 -0.43 -0.15 0.08 -0.26 -0.25 ⋯ 0.02 -0.17 -0.30 -0.41\n", "21 1 -0.51 -0.04 0.06 0.26 -0.19 -0.22 ⋯ -0.16 -0.13 -0.13 -0.03\n", "22 1 -1.01 -0.55 -0.72 -0.54 -0.55 -0.19 ⋯ -0.08 -0.25 0.12 -0.09\n", "23 1 -0.40 -0.14 -0.06 0.00 -0.22 -0.07 ⋯ -0.10 -0.15 0.03 0.09\n", "24 1 -0.19 -0.08 -0.16 -0.10 -0.12 -0.10 ⋯ -0.38 -0.19 -0.01 0.01\n", "25 1 -0.10 -0.02 -0.37 -0.09 -0.14 0.10 ⋯ -0.22 -0.04 -0.10 0.05\n", "26 1 -0.22 -0.03 -0.26 -0.19 -0.10 0.15 ⋯ -0.21 -0.16 -0.10 -0.03\n", "27 1 -0.25 -0.35 0.04 0.15 0.02 0.09 ⋯ 0.12 0.02 0.04 0.13\n", "28 1 -0.36 -0.39 0.42 -0.09 0.00 0.12 ⋯ 0.49 0.22 -0.09 -0.80\n", "29 1 0.76 0.33 -0.21 -0.16 0.00 0.09 ⋯ -0.15 -0.08 -0.72 -1.25\n", "30 1 -0.32 -0.54 -0.37 -0.64 -0.09 -0.10 ⋯ -0.56 -0.77 -0.95 -1.32\n", "⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋱ ⋮ ⋮ ⋮ ⋮ \n", "5508 1 0.09 0.23 0.13 0.27 0.11 -0.08 ⋯ 0.02 0.25 0.10 -0.03\n", "5509 1 -0.12 -0.42 -0.12 0.09 0.01 0.08 ⋯ 0.24 0.32 0.16 0.12\n", "5510 1 -1.30 0.09 0.29 -0.03 -0.14 -0.20 ⋯ 0.77 1.07 0.95 1.17\n", "5511 1 -0.16 -0.02 0.15 0.17 -0.21 -0.12 ⋯ 0.13 -0.06 -0.21 -0.11\n", "5512 1 -0.10 -0.13 0.28 0.46 0.23 -0.25 ⋯ -0.47 -0.62 -0.60 -0.51\n", "5513 1 0.13 0.17 0.53 1.21 0.38 -0.02 ⋯ -0.28 -0.11 -0.31 -0.37\n", "5514 1 0.64 0.44 1.31 1.35 0.97 0.26 ⋯ -0.13 -0.73 -0.46 -0.42\n", "5515 1 0.62 0.25 1.12 1.05 0.13 -0.12 ⋯ 0.28 0.15 -0.05 -0.29\n", "5516 1 0.63 0.59 0.73 0.65 0.23 0.29 ⋯ -0.24 -0.40 -0.42 -0.08\n", "5517 1 0.65 0.62 0.71 0.71 0.04 0.10 ⋯ -0.29 -0.56 -0.73 -0.21\n", "5518 1 0.81 0.30 0.16 0.36 0.38 0.37 ⋯ -0.07 -0.01 -0.09 0.01\n", "5519 1 0.10 -0.33 0.05 0.25 0.09 -0.05 ⋯ 0.24 0.12 -0.01 -0.05\n", "5520 1 0.01 -0.22 0.67 0.72 0.36 0.04 ⋯ -0.19 0.10 0.02 0.05\n", "5521 1 -0.01 -0.21 0.20 0.60 0.48 0.18 ⋯ -0.02 -0.06 0.07 0.03\n", "5522 1 -0.23 0.05 0.25 0.28 0.22 0.27 ⋯ -0.14 0.02 0.13 0.04\n", "5523 1 0.00 0.01 -0.13 0.02 -0.07 -0.32 ⋯ -0.09 -0.32 -0.30 -0.29\n", "5524 1 -0.22 -0.51 0.28 0.32 0.00 -0.38 ⋯ -0.49 -0.57 -0.53 -0.48\n", "5525 1 -0.10 -0.24 -0.06 -0.04 -0.37 -0.67 ⋯ -0.21 -0.16 -0.17 -0.52\n", "5526 1 0.06 -0.22 -0.09 0.15 -0.12 -0.27 ⋯ 0.15 0.16 0.03 -0.15\n", "5527 1 -0.83 0.21 0.04 -0.19 -0.41 -0.15 ⋯ 0.04 0.27 -0.17 -0.23\n", "5528 1 -0.74 -0.63 -0.07 0.11 -0.18 -0.31 ⋯ 0.26 0.11 0.04 -0.16\n", "5529 1 -0.62 -0.26 -0.19 -0.03 -0.09 -0.27 ⋯ -0.33 -0.21 -0.16 -0.20\n", "5530 1 -0.67 -0.38 -0.12 -0.05 -0.15 -0.24 ⋯ -0.12 -0.24 -0.15 -0.24\n", "5531 1 -0.14 0.06 0.78 0.81 0.30 0.14 ⋯ 0.28 0.13 0.30 0.06\n", "5532 1 0.12 -0.07 0.14 0.29 0.17 0.09 ⋯ 0.19 0.17 0.03 0.02\n", "5533 1 0.41 -0.28 0.30 0.50 -0.05 -0.08 ⋯ 0.38 0.23 0.21 0.15\n", "5534 1 0.50 -0.12 0.25 0.24 0.13 0.02 ⋯ 0.25 -0.02 -0.06 -0.10\n", "5535 1 0.15 0.09 0.21 0.46 0.19 -0.02 ⋯ 0.37 0.21 0.16 -0.01\n", "5536 1 0.63 0.38 0.05 0.12 0.13 -0.01 ⋯ -0.07 0.02 0.24 0.18\n", "5537 1 0.18 0.05 0.11 0.09 -0.02 0.03 ⋯ -0.07 -0.08 -0.02 -0.06\n", " U0.05 U0.1 U0.15 U0.2 U0.25 U0.3 \n", "1 -0.06 -0.26 -0.05 -0.28 -0.19 0.09\n", "2 -1.02 -0.91 -0.59 -0.61 -0.17 0.18\n", "3 -0.91 -0.94 -0.42 -0.36 -0.49 -0.47\n", "4 -0.53 -0.51 -0.26 0.05 -0.14 -0.01\n", "5 -0.45 -0.09 -0.13 0.02 -0.09 -0.03\n", "6 NA -0.65 0.09 0.06 -0.07 -0.10\n", "7 0.07 -0.31 -0.08 0.12 0.05 0.06\n", "8 -0.40 -0.02 0.26 0.31 0.14 0.11\n", "9 0.01 -0.16 0.07 0.20 0.02 0.10\n", "10 -0.26 -0.13 -0.10 0.07 -0.04 -0.12\n", "11 -0.02 0.04 0.16 0.02 -0.03 -0.22\n", "12 -1.15 0.41 0.28 0.00 0.17 -0.01\n", "13 -1.48 -0.43 -0.27 -0.32 -0.24 -0.15\n", "14 -1.24 0.41 0.18 0.09 0.13 -0.04\n", "15 -1.91 -0.31 0.09 -0.24 -0.03 0.19\n", "16 -1.53 -0.43 -0.46 -0.73 -0.48 -0.25\n", "17 -0.62 -0.53 -0.30 -0.17 -0.44 -0.35\n", "18 -0.80 -0.18 -0.05 -0.26 -0.58 -0.18\n", "19 -1.04 -0.59 -0.47 -0.29 -0.33 -0.20\n", "20 -0.67 -0.01 -0.20 -0.36 -0.30 -0.04\n", "21 -1.09 -0.26 0.02 -0.09 -0.43 -0.21\n", "22 NA -0.23 -0.32 -0.49 0.01 0.24\n", "23 NA -0.39 -0.30 -0.28 -0.01 0.14\n", "24 -1.07 -0.01 0.05 -0.10 -0.04 0.12\n", "25 -1.19 0.15 -0.09 -0.17 0.05 0.12\n", "26 -0.76 -0.03 -0.13 -0.20 -0.13 -0.03\n", "27 -1.10 -0.19 -0.12 0.08 0.00 0.06\n", "28 -1.59 -1.24 -0.65 -0.62 -0.61 -0.81\n", "29 -2.31 -1.70 -1.37 -1.24 -0.73 -0.83\n", "30 -5.55 -4.59 -3.34 -1.98 -3.09 -1.79\n", "⋮ ⋮ ⋮ ⋮ ⋮ ⋮ ⋮ \n", "5508 -0.13 0.56 0.39 0.38 0.40 0.36\n", "5509 0.32 0.41 0.03 -0.12 0.16 0.30\n", "5510 0.51 0.50 1.03 1.64 1.27 1.33\n", "5511 0.22 0.51 0.59 0.14 0.38 0.34\n", "5512 0.39 0.35 0.31 -0.07 0.56 0.44\n", "5513 1.21 1.54 0.93 0.50 0.52 0.27\n", "5514 3.36 2.87 2.25 2.00 2.32 1.15\n", "5515 1.95 2.00 1.40 0.50 0.81 0.64\n", "5516 0.54 1.26 0.77 0.61 0.82 0.54\n", "5517 NA 1.06 0.58 0.39 0.53 0.48\n", "5518 0.12 0.53 0.41 0.02 0.40 0.32\n", "5519 0.09 0.76 0.35 0.04 0.20 0.14\n", "5520 -0.06 0.87 0.88 0.28 0.49 0.49\n", "5521 0.49 1.47 1.13 0.04 0.69 0.32\n", "5522 0.32 0.14 -0.01 0.17 0.02 0.27\n", "5523 0.45 0.24 0.18 -0.24 -0.26 -0.08\n", "5524 0.79 1.04 0.32 -0.14 0.29 -0.16\n", "5525 -0.13 0.67 0.39 -0.11 0.33 0.09\n", "5526 0.11 0.26 -0.04 -0.24 -0.05 -0.01\n", "5527 NA 0.07 0.33 0.19 0.01 -0.34\n", "5528 -0.28 0.81 -0.10 -0.03 -0.13 -0.20\n", "5529 0.67 0.78 0.08 -0.34 -0.09 -0.21\n", "5530 0.11 0.69 0.36 -0.12 0.08 -0.04\n", "5531 -0.75 1.91 0.47 0.25 0.37 0.15\n", "5532 0.16 0.28 0.36 0.22 0.29 0.14\n", "5533 0.32 0.62 0.54 0.01 0.56 0.28\n", "5534 NA 0.50 0.29 -0.14 0.47 0.27\n", "5535 -0.68 0.63 0.41 0.09 0.48 0.43\n", "5536 -0.89 0.19 0.03 0.04 0.13 0.19\n", "5537 0.03 0.14 0.00 -0.21 0.07 0.04" ] }, "metadata": {}, "output_type": "display_data" } ], "source": [ "original_data" ] }, { "cell_type": "code", "execution_count": 17, "metadata": { "collapsed": false }, "outputs": [], "source": [ "cleaning_data_step1 <- separate(original_data, NAME, c(\"name\", \"BP\", \"MF\", \"systematic_name\", \"number\"), sep = \"\\\\|\\\\|\")" ] }, { "cell_type": "code", "execution_count": 18, "metadata": { "collapsed": false }, "outputs": [], "source": [ "cleaning_data_step2 <- mutate_each(cleaning_data_step1, funs(trimws), name:systematic_name)" ] }, { "cell_type": "code", "execution_count": 19, "metadata": { "collapsed": false }, "outputs": [], "source": [ "cleaning_data_step3 <- select(cleaning_data_step2, -number, -GID, -YORF, -GWEIGHT)" ] }, { "cell_type": "code", "execution_count": 20, "metadata": { "collapsed": false }, "outputs": [], "source": [ "cleaning_data_step4 <- gather(cleaning_data_step3, sample, expression, G0.05:U0.3)" ] }, { "cell_type": "code", "execution_count": 23, "metadata": { "collapsed": false }, "outputs": [], "source": [ "cleaning_data_step5 <- separate(cleaning_data_step4, sample, c(\"nutrient\", \"rate\"), sep =1, convert = TRUE)" ] }, { "cell_type": "code", "execution_count": 24, "metadata": { "collapsed": false }, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "Observations: 199,332\n", "Variables: 7\n", "$ name \"SFB2\", \"\", \"QRI7\", \"CFT2\", \"SSO2\", \"PSP2\", \"RIB2\",...\n", "$ BP \"ER to Golgi transport\", \"biological process unknow...\n", "$ MF \"molecular function unknown\", \"molecular function u...\n", "$ systematic_name \"YNL049C\", \"YNL095C\", \"YDL104C\", \"YLR115W\", \"YMR183...\n", "$ nutrient \"G\", \"G\", \"G\", \"G\", \"G\", \"G\", \"G\", \"G\", \"G\", \"G\", \"...\n", "$ rate 0.05, 0.05, 0.05, 0.05, 0.05, 0.05, 0.05, 0.05, 0.0...\n", "$ expression -0.24, 0.28, -0.02, -0.33, 0.05, -0.69, -0.55, -0.7...\n" ] } ], "source": [ "glimpse(cleaning_data_step5)" ] }, { "cell_type": "code", "execution_count": 32, "metadata": { "collapsed": false }, "outputs": [ { "name": "stdout", "output_type": "stream", "text": [ "# A tibble: 36 × 7\n", " name BP MF\n", " \n", "1 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "2 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "3 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "4 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "5 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "6 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "7 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "8 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "9 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "10 LEU1 leucine biosynthesis 3-isopropylmalate dehydratase activity\n", "# ... with 26 more rows, and 4 more variables: systematic_name ,\n", "# nutrient , rate , expression \n" ] } ], "source": [ "data.filtered <- filter(cleaning_data_step5, name == \"LEU1\")\n", "print(data.filtered)" ] }, { "cell_type": "code", "execution_count": 33, "metadata": { "collapsed": false }, "outputs": [ { "data": {}, "metadata": {}, "output_type": "display_data" }, { "data": { "image/png": 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ewQ6BTVYDCnG8zppz/kW+Rz2I467Q0O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\n5c7ia/6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ZUxwc6V3n6rba/dujvaHJtX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\n3Nzc0z347rvvXrZs2cUXX5zMCgHO23BO70gk8sQTT2zevDkcDldVVS1ZsmT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"text/plain": [ "plot without title" ] }, "metadata": {}, "output_type": "display_data" } ], "source": [ "ggplot(data = data.filtered) + geom_line(mapping = aes(x = rate, y = expression, color = nutrient))" ] }, { "cell_type": "code", "execution_count": null, "metadata": { "collapsed": true }, "outputs": [], "source": [] } ], "metadata": { "kernelspec": { "display_name": "R (SageMath)", "language": "r", "name": "ir-sage" }, "language_info": { "codemirror_mode": "r", "file_extension": ".r", "mimetype": "text/x-r-source", "name": "R", "pygments_lexer": "r", "version": "3.2.4" } }, "nbformat": 4, "nbformat_minor": 0 }