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#1 # No CF CF #test + 99.9667 (9996.67 - 9896.7033) 2.89(3.333*0.87) #test - 9896.7033 (0.99*9996.67) 0.433 (3.333-2.89) #total 9996.67 3.333 (1/3000*10000) #Sensitivity is 87% #Specificity is 99% #USed 10000 as sample size
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#1a #2.89/(99.9667+2.89) = 2.809% of a newborn actually having CF is that they have a blood test #Positive predictive value: 0.87*0.003/ ((0.87*0.003 + (0.99*99.9996))) = 0.028999351469048962 #Prevalence = 1/3000
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0.87*0.0003/ ((0.87*0.0003 + (0.99*99.9996)))
2.636367231409861e-06
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#1b The test gives a high specificity which can ensure that the baby most likely doesn't have CF, if they really don't have it. The test ensures that it can detect CF before the condition worsens.Althought, the sensitivity is not as high, the test is used more to detect`
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#2a # No COVID COVID-19 #test + 939.99 (9999.99-9059.99) 0.887 (1*0.887) #test - 9059.35 (0.906*9999.99) 0.113 (1-0.887) #total 9999.99 (1-10000) 1 (1/10000 *10000) #Sensitivity is 88.7% #Specificity is 90.6% #Used 10000 as sample size #0.887/(939.99+0.887) = 0.0942% who test positive (0.887/(939.99+0.887))*100
0.09427374672778695
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#2B #Using the positive predictive value, we see that a person that tests positive and actually has the COVID-19 is a 0.094% chance. Compared to a person who actually has a fever and cough, we can predict that this patient has a higher chance of carrying the disease compared to the person that tested for COVID-19.
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#2C # No COVID COVID-19 #test + 921.2 (9800-8878.8) 177.4 (200*0.887) #test - 8878.8 (9800*0.906) 22.6 (200-177.4) #total 9800 (200-10000) 200 (1/50 *10000) #Sensitivity is 88.7% #Specificity is 90.6% #Used 10000 as sample size (177.4/(921.2+177.4)) #
0.1614782450391407
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#3 # Model X Model Y # Allele B 26.4 ((0.66*40)/1) 3.3 ((0.33*10)/1) # Allele D 39.6 ((0.66*60)/1) 29.7 ((0.33*90)/1) #Prevalence of Model X is 66% # prevalence of Model Y is 33% #Observing the B allele, the new values of probability of Model X is 26.4 and Model Y is 3.3. The observed new values for the D allele in Model X is 39.6 and Model Y is 29.
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